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Menopausal hormone therapy may increase risk of ovarian cancer, research suggests

Date:
November 12, 2010
Source:
American Association for Cancer Research
Summary:
Women planning on taking hormone therapy for the treatment of menopausal symptoms should be aware of a possible increased risk for ovarian cancer, according to new research.

Women planning on taking hormone therapy for the treatment of menopausal symptoms should be aware of a possible increased risk for ovarian cancer, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10 in Philadelphia.

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"This study is consistent with previous recommendations that say if women are going to take hormones they should only take them in the short term," said Konstantinos Tsilidis, Ph.D., a postdoctoral fellow at the Cancer Epidemiology Unit at the University of Oxford.

Tsilidis and colleagues analyzed the European Prospective Investigation into Cancer and Nutrition, which included 126,920 women, of whom 424 were diagnosed with ovarian cancer over nine years of follow-up.

Although former use of hormone therapy was not associated with increased risk, current use of hormone therapy was linked with a 29 percent increased risk.

Risk levels did not differ by type of hormone therapy (estrogen only vs. estrogen plus progestin), specific hormonal constituents, regimens and routes of administration of hormone therapy, or by ovarian cancer histology.


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The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


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American Association for Cancer Research. "Menopausal hormone therapy may increase risk of ovarian cancer, research suggests." ScienceDaily. ScienceDaily, 12 November 2010. <www.sciencedaily.com/releases/2010/11/101109133134.htm>.
American Association for Cancer Research. (2010, November 12). Menopausal hormone therapy may increase risk of ovarian cancer, research suggests. ScienceDaily. Retrieved March 28, 2015 from www.sciencedaily.com/releases/2010/11/101109133134.htm
American Association for Cancer Research. "Menopausal hormone therapy may increase risk of ovarian cancer, research suggests." ScienceDaily. www.sciencedaily.com/releases/2010/11/101109133134.htm (accessed March 28, 2015).

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