Featured Research

from universities, journals, and other organizations

Smoking during pregnancy affects myelin genes in offspring

Date:
November 15, 2010
Source:
Society for Neuroscience
Summary:
Smoking during pregnancy may interfere with brain development. New animal research shows maternal smoking affects genes important in the formation and action of a fatty brain substance called myelin that insulates brain cell connections.

Smoking during pregnancy may interfere with brain development. New animal research shows maternal smoking affects genes important in the formation and action of a fatty brain substance called myelin that insulates brain cell connections.

Related Articles


The research was presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience, held in San Diego.

The finding may explain why the children of mothers who smoked during pregnancy are more likely to develop attention deficit hyperactivity disorder, depression, autism, drug abuse, and other psychiatric disorders. "Myelin deficits have been previously observed in adults with various psychiatric disorders," said Ming Li, PhD, of the University of Virginia, who directed the study. "Our findings suggest that abnormal myelination may also contribute to the psychiatric disorders associated with maternal smoking," Li said.

The study found that when rats were given nicotine during pregnancy, their offspring showed changes in myelin genes in specific regions of their brain's limbic system -- structures involved with emotion. The effect was strongest in the prefrontal cortex, a brain region important for decision-making.

The researchers also identified sex differences in nicotine's effects. Myelin-related genes increased in the prefrontal cortex of the male offspring, but decreased in the females. The opposite was observed in the hypothalamic paraventricular nucleus, a brain region involved in the regulation of stress and appetite, among other functions.

"These findings suggest that maternal smoking may affect daughters and sons differently," Li said. Research was supported by the National Institute on Drug Abuse.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "Smoking during pregnancy affects myelin genes in offspring." ScienceDaily. ScienceDaily, 15 November 2010. <www.sciencedaily.com/releases/2010/11/101115155331.htm>.
Society for Neuroscience. (2010, November 15). Smoking during pregnancy affects myelin genes in offspring. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2010/11/101115155331.htm
Society for Neuroscience. "Smoking during pregnancy affects myelin genes in offspring." ScienceDaily. www.sciencedaily.com/releases/2010/11/101115155331.htm (accessed October 24, 2014).

Share This



More Mind & Brain News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins