Featured Research

from universities, journals, and other organizations

Desensitization approaches effective against hayfever-like allergies, research suggests

Date:
December 8, 2010
Source:
Wiley-Blackwell
Summary:
Immunotherapy given as pills or drops under the tongue is a safe and effective way to treat hayfever-like allergies caused by pollen and dust mites, according to a new review. The researchers say the approach is an attractive alternative to immunotherapy injections in children.

Immunotherapy given as pills or drops under the tongue is a safe and effective way to treat hayfever-like allergies caused by pollen and dust mites, according to a new Cochrane Systematic Review. The researchers say the approach is an attractive alternative to immunotherapy injections in children.

Common treatments for hayfever-like symptoms caused by allergies include antihistamines and nasal corticosteroids. If these prove unsuccessful, doctors may recommend immunotherapy, a desensitisation approach that involves exposing patients to increasing doses of an allergen. Traditionally immunotherapy was carried out by injection, but allergens are now also applied as pills or drops under the tongue.

Although a 2003 Cochrane review suggested sublingual immunotherapy was effective, the findings were based on a relatively small number of trials. Much more evidence is now available and the researchers were able to add another 38 studies to their current review, totalling 60 altogether. They included trials of pollen and dust mites, as well as one trial of cat allergens. Sublingual immunotherapy significantly reduced symptoms of allergic rhinitis and requirements for medication compared to placebos. The results confirm the treatment is effective and has very few serious adverse effects.

The larger number of trials allowed the researchers to make stronger recommendations for use of sublingual immunotherapy in children. "This is an attractive approach for treating allergies in children. It is a more convenient alternative compared to injection immunotherapy," said Suzana Radulovic, one of the review authors, who is currently based at the Paediatric Allergy Research Department at St Thomas' Hospital in London, UK. "It is encouraging to see similar treatment effects in children compared to those in adults."

Overall, treatment effects comparable to those seen in the previous review provide greater reassurance for clinical practitioners. "Sublingual immunotherapy is an effective treatment for allergic rhinitis. With the inclusion of larger, better designed trials, we can be much more confident about the results," said Radulovic. "What we'd like to see now is more work on optimum dosage and treatment times."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "Desensitization approaches effective against hayfever-like allergies, research suggests." ScienceDaily. ScienceDaily, 8 December 2010. <www.sciencedaily.com/releases/2010/12/101207191445.htm>.
Wiley-Blackwell. (2010, December 8). Desensitization approaches effective against hayfever-like allergies, research suggests. ScienceDaily. Retrieved August 23, 2014 from www.sciencedaily.com/releases/2010/12/101207191445.htm
Wiley-Blackwell. "Desensitization approaches effective against hayfever-like allergies, research suggests." ScienceDaily. www.sciencedaily.com/releases/2010/12/101207191445.htm (accessed August 23, 2014).

Share This




More Health & Medicine News

Saturday, August 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins