Featured Research

from universities, journals, and other organizations

Asthma? Allergens could be growing in your lungs

Date:
December 15, 2010
Source:
University of Leicester
Summary:
Scientists investigating the allergic reactions that asthmatics suffer towards a common mold have discovered that many people with asthma actually had the mold growing in their own lungs.

Scientists investigating the allergic reactions that asthmatics suffer towards a common mould have discovered that many people with asthma actually had the mould growing in their own lungs.

The research led by University of Leicester scientists at Glenfield Hospital has been published in the December 2010 issue of the American Journal of Respiratory and Critical Care Medicine.

The team based in the Institute for Lung Health at the University of Leicester and Glenfield Hospital examined the impact on asthmatics of a common environmental mould, Aspergillus fumigates, usually found in soil and compost heaps.

Professor Andy Wardlaw from the University of Leicester said: "Asthma is a very common condition where the breathing tubes (bronchi) can go into spasm making it difficult to breathe. Around a fifth of adults with severe asthma, which they have had for a long time, get permanent (fixed) narrowing of their bronchi. It is known that A. fumigatus can grow in the lungs of some people with asthma and mould allergy, which can cause severe lung damage.

"This problem is thought to only affect a very small number of people with asthma; however, about half of people with severe asthma have evidence of allergy to moulds like A. fumigatus."

Researchers in the Institute for Lung Health at the University of Leicester and Glenfield Hospital, Leicester, carried out a study funded by the Midlands Asthma and Allergy Research Association (MAARA, a Midlands based charity funding research into asthma and allergy research) and the European Regional Development Fund (ERDF), to determine whether the problem of A. fumigatus growing in the lungs is more common than previously thought, and whether this could explain the fixed narrowing of the airways that occurs in some people with asthma.

Professor Wardlaw added: "Our study showed that 6 out of 10 people with asthma who were allergic to A. fumigatus grew the mould from their sputum. We also found that if you were allergic to A. fumigatus you had more narrowing of the airways than if you were not allergic, and this was worse in patients from whom A. fumigatus was grown.

"Our research concluded that it is possible that fixed narrowing of breathing tubes in many people with asthma could be caused by A. fumigatus growing in their lungs.

"Treating individuals from whom A. fumigatus is detected with antibiotics against the mouldmay prevent fixed narrowing of the airways."


Story Source:

The above story is based on materials provided by University of Leicester. Note: Materials may be edited for content and length.


Journal Reference:

  1. Abbie Fairs, Joshua Agbetile, Beverley Hargadon, Michelle Bourne, William R. Monteiro, Christopher E. Brightling, Peter Bradding, Ruth H. Green, Kugathasan Mutalithas, Dhananjay Desai, Ian D. Pavord1, Andrew J. Wardlaw and Catherine H. Pashley. IgE Sensitization to Aspergillus fumigatus Is Associated with Reduced Lung Function in Asthma. American Journal of Respiratory and Critical Care Medicine, December 2010

Cite This Page:

University of Leicester. "Asthma? Allergens could be growing in your lungs." ScienceDaily. ScienceDaily, 15 December 2010. <www.sciencedaily.com/releases/2010/12/101214085736.htm>.
University of Leicester. (2010, December 15). Asthma? Allergens could be growing in your lungs. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2010/12/101214085736.htm
University of Leicester. "Asthma? Allergens could be growing in your lungs." ScienceDaily. www.sciencedaily.com/releases/2010/12/101214085736.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
West Africa Gripped by Deadly Ebola Outbreak

West Africa Gripped by Deadly Ebola Outbreak

AFP (July 28, 2014) The worst-ever outbreak of the deadly Ebola epidemic grips west Africa, killing hundreds. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins