Featured Research

from universities, journals, and other organizations

Smoking may be associated with increased risk of breast cancer

Date:
January 25, 2011
Source:
JAMA and Archives Journals
Summary:
Smoking before menopause, especially prior to giving birth, may be associated with a modest increase in the risk of developing breast cancer, according to a new study.

Smoking before menopause, especially prior to giving birth, may be associated with a modest increase in the risk of developing breast cancer, according to a report in the January 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

"Breast cancer is the most common cancer to affect women worldwide," according to background information in the article. "Tobacco smoke contains potential human breast carcinogens, including polycyclic aromatic hydrocarbons, aromatic amines and N-nitrosamines."

Using data collected from the Nurses' Health Study, Fei Xue, M.D., Sc.D., of Brigham and Woman's Hospital and Harvard Medical School, Boston, and colleagues examined the records of 111,140 women from 1976 to 2006 for active smoking and 36,017 women from 1982 to 2006 for passive (secondhand) smoking.

A total of 8,772 breast cancer cases developed during follow-up. The development of breast cancer was associated with a higher quantity of current and past smoking, smoking for a longer period of time, younger age at smoking initiation and more pack-years (product of the number of packs per day and the number of years that quantity was smoked) of smoking.

"Smoking before menopause was positively associated with breast cancer risk, and there were hints from our results that smoking after menopause might be associated with a slightly decreased breast cancer risk," the authors write. "This difference suggests an antiestrogenic effect of smoking among postmenopausal women that may further reduce their already low endogenous estrogen levels."

Conversely, never smoking and passive smoking in childhood or adulthood were not associated with an increase in breast cancer risk. Exposure to parents who smoked while living in the same house, passive smoking while at work or at home and the number of years living with someone who smoked were not related to increased risk of breast cancer after adjusting for other possible factors.

"In the present study, we created an index of active smoking that integrates quantity, age at which one started smoking and duration of smoking," the authors conclude. "The results suggested that, although an elevated risk for light smokers and moderate smokers was not apparent, heavy smokers who started smoking early in life, smoked for a long duration and smoked a high quantity were at the highest risk of breast cancer, supporting an independent and additive effect from various smoking measures on breast carcinogenesis."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. F. Xue, W. C. Willett, B. A. Rosner, S. E. Hankinson, K. B. Michels. Cigarette Smoking and the Incidence of Breast Cancer. Archives of Internal Medicine, 2011; 171 (2): 125 DOI: 10.1001/archinternmed.2010.503

Cite This Page:

JAMA and Archives Journals. "Smoking may be associated with increased risk of breast cancer." ScienceDaily. ScienceDaily, 25 January 2011. <www.sciencedaily.com/releases/2011/01/110124162619.htm>.
JAMA and Archives Journals. (2011, January 25). Smoking may be associated with increased risk of breast cancer. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2011/01/110124162619.htm
JAMA and Archives Journals. "Smoking may be associated with increased risk of breast cancer." ScienceDaily. www.sciencedaily.com/releases/2011/01/110124162619.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins