Featured Research

from universities, journals, and other organizations

Kidney transplant recipients: Get moving to save your life

Date:
March 3, 2011
Source:
American Society of Nephrology
Summary:
Low physical activity increases kidney transplant patients' likelihood of dying early, according to a new study. The results suggest that patients need to exercise to fend off an early death.

Low physical activity increases kidney transplant patients' likelihood of dying early, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that patients need to exercise to fend off an early death.

Inactive people in general face increased risks of developing cardiovascular disease and of dying prematurely. Individuals with chronic kidney disease -- particularly those on dialysis -- tend to get little exercise, but most increase their activity levels modestly after receiving a kidney transplant. Until now, no one has examined whether low physical activity levels in kidney transplant recipients is associated with an increased risk of dying prematurely from heart-related or other causes. Maintaining heart health is particularly important for these individuals, as kidney transplant recipients have a 4- to 6-fold increased risk of dying from cardiovascular causes than individuals in the general population.

Dorien Zelle (University Medical Center Groningen, in the Netherlands) and her colleagues studied the health of 540 kidney transplant recipients between 2001 and 2003, assessing physical activity through questionnaires and recording deaths until August 2007. With regard to the guidelines for minimum requirements of physical activity, 260 (48%) patients did not meet the criteria and 79 (14.6%) were completely inactive.

During the study period, 81 patients died, with 37 heart-related deaths; the lower the level of physical activity, the higher the rate of deaths. Specifically, cardiovascular deaths occurred in 11.7%, 7.2%, and 1.7% of patients considered inactive, moderately active, and active, respectively. Deaths from any cause occurred at rates of 24.4%, 15.0%, and 5.6% in these respective groups.

The investigators acknowledged that in general, sicker people are less likely to exercise and more likely to die; however, they found that the link between low physical activity and premature death was not substantially affected by adjustments for factors such as patients' heart health, kidney function, muscle mass, and their diabetes and smoking status.

Dr. Zelle noted that to determine whether increased physical activity levels may improve the health and prolong the lives of transplant recipients, the University Medical Center Groningen, in collaboration with the University Medical Center Maastricht, will start a randomized controlled lifestyle intervention study. Kidney transplant recipients will undergo a supervised exercise program and receive individual counseling to promote physical activity and a healthy diet.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Dorien Zelle, Eva Corpeleijn, Ronald Stolk, Mathieu de Greef, Reinold Gans, Gerjan Navis, and Stephan Bakker et al. Low Physical Activity Is Associated with Increased Risk for Cardiovascular and All-Cause Mortality in Renal Transplant Recipients. Clinical Journal of the American Society Nephrology, March 3, 2011 DOI: 10.2215/CJN.03340410

Cite This Page:

American Society of Nephrology. "Kidney transplant recipients: Get moving to save your life." ScienceDaily. ScienceDaily, 3 March 2011. <www.sciencedaily.com/releases/2011/03/110303184105.htm>.
American Society of Nephrology. (2011, March 3). Kidney transplant recipients: Get moving to save your life. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2011/03/110303184105.htm
American Society of Nephrology. "Kidney transplant recipients: Get moving to save your life." ScienceDaily. www.sciencedaily.com/releases/2011/03/110303184105.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins