Featured Research

from universities, journals, and other organizations

Fractal dimension analysis aids breast cancer prognosis

Date:
April 25, 2011
Source:
University of Calgary
Summary:
Cancer researchers are investigating a new tool to use for the prognosis of breast cancer in patients. The scientists are using fractal dimension analysis to quantitatively assess the degree of abnormality and aggressiveness of breast cancer tumors obtained through biopsy.

Mauro Tambasco, Ph.D., analyzes breast tissue samples on his computer.
Credit: Bruce Perrault

Cancer researchers at the University of Calgary are investigating a new tool to use for the prognosis of breast cancer in patients. This new digital tool will help give patients a more accurate assessment of how abnormal and aggressive their cancer is and help doctors recommend the best treatment options.

Related Articles


Currently, a useful factor for deciding the best treatment strategy for early-stage breast cancer is tumour grade, a score assigned by a pathologist based on how abnormal cancer cells from a patient tissue sample look under the microscope. However, tumour grade is somewhat subjective and can vary between pathologists. Hence, there is a need for more objective methods to assess cancer tissue, which could improve risk assessment and therapeutic decisions.

Using a mathematical computer program developed at the U of C , Mauro Tamabsco, PhD, and his team used fractal dimension analysis to quantitatively assess the degree of abnormality and aggressiveness of breast cancer tumours obtained through biopsy. Fractal analysis of images of breast tissue specimens provides a numeric description of tumour growth patterns as a continuous number between 1 and 2. This number, the fractal dimension, is an objective and reproducible measure of the complexity of the tissue architecture of the biopsy specimen. The higher the number, the more abnormal the tissue is.

According to the team's published study, this novel method of analysis is more accurate and objective than pathological grade. "This new technology is not meant to replace pathologists, but is just a new digital tool for them to use" says Tambasco, a medical physicist at the University of Calgary Faculty of Medicine and the Tom Baker Cancer Center.

Researchers say they will continue to study this new digital method and hope in the next few years that it could become another tool used in the clinical setting.

The retrospective study analysed tissue specimens from 379 breast cancer patients and the findings were published in the January 2011 edition of the Journal of Translational Medicine.


Story Source:

The above story is based on materials provided by University of Calgary. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mauro Tambasco, Misha Eliasziw, Anthony M Magliocco. Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival. Journal of Translational Medicine, 2010; 8 (1): 140 DOI: 10.1186/1479-5876-8-140

Cite This Page:

University of Calgary. "Fractal dimension analysis aids breast cancer prognosis." ScienceDaily. ScienceDaily, 25 April 2011. <www.sciencedaily.com/releases/2011/04/110418093852.htm>.
University of Calgary. (2011, April 25). Fractal dimension analysis aids breast cancer prognosis. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2011/04/110418093852.htm
University of Calgary. "Fractal dimension analysis aids breast cancer prognosis." ScienceDaily. www.sciencedaily.com/releases/2011/04/110418093852.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins