Featured Research

from universities, journals, and other organizations

Experts question whether preventive drugs are value for money

Date:
April 19, 2011
Source:
BMJ-British Medical Journal
Summary:
Writing in a new article, experts challenge the view that popular drugs to prevent disease -- like statins and anti-hypertensives to prevent heart disease and stroke, or bisphosphonates to prevent fractures -- represent value for money.

Experts are challenging the view that popular drugs to prevent disease -- like statins and antihypertensives to prevent heart disease and stroke, or bisphosphonates to prevent fractures -- represent value for money.

Related Articles


In a paper published online in the British Medical Journal, Teppo Jδrvinen and colleagues argue that the benefits seen when these drugs are tested in clinical trials may not apply in the real world.

They argue that value for money in real life clinical practice is likely to be much lower than in a clinical trial, where patients are carefully selected and receive special attention from dedicated staff. "This gap between the ideal and clinical circumstances raises the question of how well our most widely used preventive drugs work in real life," they write.

For example, data from randomised trials suggest that bisphosphonates are a cost effective way to prevent hip fractures in older people. But this is a far cry from reality, say the authors.

Using 2003 data on 7411 hip fractures in Finland, they estimate that giving bisphosphonates to all 1.86 million citizens aged 50 years and over would only guarantee prevention of 343 fractures.

"Thus, although there are claims that important preventive drugs such as statins, antihypertensives, and bisphosphonates are cost effective, there are no valid data on the effectiveness, and particularly the cost effectiveness, in usual clinical care," they say.

Despite this dearth of data, they point out that the majority of clinical guidelines and recommendations for preventive drug therapy rest on these claims.

The authors argue that before claims on cost effectiveness can be used to guide treatment policies and practices, it should be adequately proven by testing in a real-world setting.

"We need to put an end to this kind of gaming of the system and start to advocate true comparative effectiveness research," they conclude. "Unless this is done, the important question whether preventive pharmacotherapy is cost effective will remain unanswered."


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. L. N. Jarvinen, H. Sievanen, P. Kannus, J. Jokihaara, K. M. Khan. The true cost of pharmacological disease prevention. BMJ, 2011; 342 (apr19 1): d2175 DOI: 10.1136/bmj.d2175

Cite This Page:

BMJ-British Medical Journal. "Experts question whether preventive drugs are value for money." ScienceDaily. ScienceDaily, 19 April 2011. <www.sciencedaily.com/releases/2011/04/110419205723.htm>.
BMJ-British Medical Journal. (2011, April 19). Experts question whether preventive drugs are value for money. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2011/04/110419205723.htm
BMJ-British Medical Journal. "Experts question whether preventive drugs are value for money." ScienceDaily. www.sciencedaily.com/releases/2011/04/110419205723.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Science & Society News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Why So Many People Think NASA's Asteroid Mission Is A Waste

Why So Many People Think NASA's Asteroid Mission Is A Waste

Newsy (Mar. 27, 2015) — The Asteroid Retrieval Mission announced this week bears little resemblance to its grand beginnings. Even NASA scientists are asking, "Why bother?" Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
Indiana Permits Needle Exchange as HIV Cases Skyrocket

Indiana Permits Needle Exchange as HIV Cases Skyrocket

Reuters - US Online Video (Mar. 26, 2015) — Governor Mike Pence declares the recent HIV outbreak in rural Indiana a "public health emergency" and authorizes a short-term needle-exchange program. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) — While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Science & Society

Business & Industry

Education & Learning

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins