Featured Research

from universities, journals, and other organizations

Obesity in pregnancy hinders women's ability to fight infection

Date:
May 11, 2011
Source:
American Academy of Pediatrics
Summary:
Pregnant women who are obese are less able to fight infections than lean women, which could affect their baby's health after birth and later in life.

Pregnant women who are obese are less able to fight infections than lean women, which could affect their baby's health after birth and later in life, according to research presented on May 1, at the Pediatric Academic Societies (PAS) annual meeting in Denver.

"Women who are obese before pregnancy have critical differences in their immune function during pregnancy compared to normal weight women, which has negative consequences for both mother and baby," said Sarbattama Sen, MD, lead author of the study and a researcher in the Mother Infant Research Institute at Tufts Medical Center and Floating Hospital for Children in Boston.

Obesity in pregnancy has been associated with an increase in infections such as chorioamnionitis, a condition in which the membranes surrounding the fetus and the amniotic fluid are infected. This can have serious consequences for both the mother and the baby.

Dr. Sen and colleagues from the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University sought to determine whether obesity in pregnancy changes women's ability to fight off infections. They drew blood from 30 women who were 24-28 weeks pregnant to measure the presence of different cells and cell proteins that help fight infections. Fifteen women were obese before they became pregnant (body mass index higher than 30), and fifteen women had a normal body mass index (20-25).

Results showed that obese women had fewer CD8+ (cytotoxic T) cells and natural killer cells, which help fight infection, compared to lean women. In addition, obese pregnant women's ability to produce cells to fight infection was impaired.

"Maternal obesity has consequences for the mother and baby, which we are only beginning to understand," Dr. Sen concluded. "As the numbers of obese women of reproductive age increase, it is critical to understand the repercussions of this disease for future generations."


Story Source:

The above story is based on materials provided by American Academy of Pediatrics. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Pediatrics. "Obesity in pregnancy hinders women's ability to fight infection." ScienceDaily. ScienceDaily, 11 May 2011. <www.sciencedaily.com/releases/2011/05/110501183657.htm>.
American Academy of Pediatrics. (2011, May 11). Obesity in pregnancy hinders women's ability to fight infection. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2011/05/110501183657.htm
American Academy of Pediatrics. "Obesity in pregnancy hinders women's ability to fight infection." ScienceDaily. www.sciencedaily.com/releases/2011/05/110501183657.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins