Featured Research

from universities, journals, and other organizations

Fracture prediction methods may be useful for patients with diabetes

Date:
May 31, 2011
Source:
JAMA and Archives Journals
Summary:
Use of established fracture prediction methods in older patients with Type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a new study.

Use of established fracture prediction methods in older patients with type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a study in the June 1 issue of JAMA. Because patients with type 2 DM often have higher levels of bone mineral density (BMD), it has been uncertain the applicability of fracture risk screening methods typically used for patients with lower levels of BMD.

"It is increasingly recognized that adults with type 2 diabetes mellitus, an estimated 17 percent of older adults in the United States, have a higher fracture rate. Preventive identification of adults at higher fracture risk is based on bone mineral density T scores, used alone or in the World Health Organization Fracture Risk Algorithm (FRAX) score," according to background information in the article. "There is a need to clarify the use of standard methods for assessing fracture risk in this expanding population of older adults [with type 2 DM]."

Ann V. Schwartz, Ph.D., of the University of California, San Francisco and colleagues conducted a study to assess the associations of BMD T score and FRAX score with hip and nonspine fracture risk in older adults with type 2 DM. The researchers analyzed data from 3 prospective observational studies with fracture outcomes that included 9,449 women and 7,436 men.

Of 770 women with DM, 84 experienced a hip fracture and 262 a nonspine fracture during an average follow-up of 12.6 years. Of 1,199 men with DM, 32 experienced a hip fracture and 133 a nonspine fracture during an average follow-up of 7.5 years. The researchers found that femoral neck (segment of bone connecting the head of the femur and the shaft) BMD T score and FRAX score were associated with hip and nonspine fracture risk in patients with DM. "However, for a given T score and age, those adults with DM had a higher risk of fracture than those without DM, consistent with previous studies. Participants with DM also experienced higher fracture rates at a given FRAX score than participants without DM," the authors write.

"Our results indicate that femoral neck BMD and the FRAX score are as useful for the assessment of fracture risk in older adults with DM as in those without DM. However, interpretation of T score or FRAX score in an older patient with DM must take into account the higher fracture risk associated with DM," the researchers write. "Refinements are needed in current treatment and diagnostic algorithms for use in older patients with type 2 DM."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ann V. Schwartz, Eric Vittinghoff, Douglas C. Bauer, Teresa A. Hillier, Elsa S. Strotmeyer, Kristine E. Ensrud, Meghan G. Donaldson, Jane A. Cauley, Tamara B. Harris, Annemarie Koster, Catherine R. Womack, Lisa Palermo, Dennis M. Black, for the Study of Osteoporotic Fractures (SOF), the Osteoporotic Fractures in Men (MrOS), and the Health, Aging, and Body Composition (Health ABC) Research Groups. Association of BMD and FRAX Score With Risk of Fracture in Older Adults With Type 2 Diabetes. JAMA, 2011; 305 (21): 2184-2192 DOI: 10.1001/jama.2011.715

Cite This Page:

JAMA and Archives Journals. "Fracture prediction methods may be useful for patients with diabetes." ScienceDaily. ScienceDaily, 31 May 2011. <www.sciencedaily.com/releases/2011/05/110531162136.htm>.
JAMA and Archives Journals. (2011, May 31). Fracture prediction methods may be useful for patients with diabetes. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2011/05/110531162136.htm
JAMA and Archives Journals. "Fracture prediction methods may be useful for patients with diabetes." ScienceDaily. www.sciencedaily.com/releases/2011/05/110531162136.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins