Featured Research

from universities, journals, and other organizations

Fracture prediction methods may be useful for patients with diabetes

Date:
May 31, 2011
Source:
JAMA and Archives Journals
Summary:
Use of established fracture prediction methods in older patients with Type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a new study.

Use of established fracture prediction methods in older patients with type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a study in the June 1 issue of JAMA. Because patients with type 2 DM often have higher levels of bone mineral density (BMD), it has been uncertain the applicability of fracture risk screening methods typically used for patients with lower levels of BMD.

"It is increasingly recognized that adults with type 2 diabetes mellitus, an estimated 17 percent of older adults in the United States, have a higher fracture rate. Preventive identification of adults at higher fracture risk is based on bone mineral density T scores, used alone or in the World Health Organization Fracture Risk Algorithm (FRAX) score," according to background information in the article. "There is a need to clarify the use of standard methods for assessing fracture risk in this expanding population of older adults [with type 2 DM]."

Ann V. Schwartz, Ph.D., of the University of California, San Francisco and colleagues conducted a study to assess the associations of BMD T score and FRAX score with hip and nonspine fracture risk in older adults with type 2 DM. The researchers analyzed data from 3 prospective observational studies with fracture outcomes that included 9,449 women and 7,436 men.

Of 770 women with DM, 84 experienced a hip fracture and 262 a nonspine fracture during an average follow-up of 12.6 years. Of 1,199 men with DM, 32 experienced a hip fracture and 133 a nonspine fracture during an average follow-up of 7.5 years. The researchers found that femoral neck (segment of bone connecting the head of the femur and the shaft) BMD T score and FRAX score were associated with hip and nonspine fracture risk in patients with DM. "However, for a given T score and age, those adults with DM had a higher risk of fracture than those without DM, consistent with previous studies. Participants with DM also experienced higher fracture rates at a given FRAX score than participants without DM," the authors write.

"Our results indicate that femoral neck BMD and the FRAX score are as useful for the assessment of fracture risk in older adults with DM as in those without DM. However, interpretation of T score or FRAX score in an older patient with DM must take into account the higher fracture risk associated with DM," the researchers write. "Refinements are needed in current treatment and diagnostic algorithms for use in older patients with type 2 DM."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ann V. Schwartz, Eric Vittinghoff, Douglas C. Bauer, Teresa A. Hillier, Elsa S. Strotmeyer, Kristine E. Ensrud, Meghan G. Donaldson, Jane A. Cauley, Tamara B. Harris, Annemarie Koster, Catherine R. Womack, Lisa Palermo, Dennis M. Black, for the Study of Osteoporotic Fractures (SOF), the Osteoporotic Fractures in Men (MrOS), and the Health, Aging, and Body Composition (Health ABC) Research Groups. Association of BMD and FRAX Score With Risk of Fracture in Older Adults With Type 2 Diabetes. JAMA, 2011; 305 (21): 2184-2192 DOI: 10.1001/jama.2011.715

Cite This Page:

JAMA and Archives Journals. "Fracture prediction methods may be useful for patients with diabetes." ScienceDaily. ScienceDaily, 31 May 2011. <www.sciencedaily.com/releases/2011/05/110531162136.htm>.
JAMA and Archives Journals. (2011, May 31). Fracture prediction methods may be useful for patients with diabetes. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2011/05/110531162136.htm
JAMA and Archives Journals. "Fracture prediction methods may be useful for patients with diabetes." ScienceDaily. www.sciencedaily.com/releases/2011/05/110531162136.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins