Featured Research

from universities, journals, and other organizations

Threshold hemoglobin and mortality in people with stable coronary disease

Date:
May 31, 2011
Source:
Public Library of Science
Summary:
In a new study, researchers report that, in people with stable coronary disease, there were threshold haemoglobin values below which mortality increased in a graded, continuous fashion.

In a new article in PLoS Medicine, Anoop Shah of University College London and colleagues report that, in people with stable coronary disease, there were threshold haemoglobin values below which mortality increased in a graded, continuous fashion. As well as a systematic review and statistical analysis of previous studies, the researchers conducted a retrospective analysis of patients from a prospective observational cohort.

Their findings suggest that there are thresholds of haemoglobin that are associated with increased risk of mortality in patients with angina or myocardial infarction, and, though limited by the observational nature of its results, the study supports the rationale for conducting future randomised controlled trials to assess whether haemoglobin levels are causal and whether clinicians should intervene to increase haemoglobin levels, for example by oral iron supplementation.

The authors say that "Irrespective of a possible causal, reversible relationship between

haemoglobin concentration and mortality, further research is warranted to assess what incremental prognostic value haemoglobin might offer in risk stratifying patients with stable coronary disease."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Anoop D. Shah, Owen Nicholas, Adam D. Timmis, Gene Feder, Keith R. Abrams, Ruoling Chen, Aroon D. Hingorani, Harry Hemingway. Threshold Haemoglobin Levels and the Prognosis of Stable Coronary Disease: Two New Cohorts and a Systematic Review and Meta-Analysis. PLoS Medicine, 2011; 8 (5): e1000439 DOI: 10.1371/journal.pmed.1000439

Cite This Page:

Public Library of Science. "Threshold hemoglobin and mortality in people with stable coronary disease." ScienceDaily. ScienceDaily, 31 May 2011. <www.sciencedaily.com/releases/2011/05/110531180932.htm>.
Public Library of Science. (2011, May 31). Threshold hemoglobin and mortality in people with stable coronary disease. ScienceDaily. Retrieved July 26, 2014 from www.sciencedaily.com/releases/2011/05/110531180932.htm
Public Library of Science. "Threshold hemoglobin and mortality in people with stable coronary disease." ScienceDaily. www.sciencedaily.com/releases/2011/05/110531180932.htm (accessed July 26, 2014).

Share This




More Health & Medicine News

Saturday, July 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins