Featured Research

from universities, journals, and other organizations

Cognitive impairment seen in preschool children with epilepsy, study finds

Date:
June 3, 2011
Source:
Wiley-Blackwell
Summary:
A recent study has shown that cognitive impairment is evident early on in preschool children with epilepsy, consistent with results of similar studies in older children. Age of onset of first seizure is a significant predictor of cognitive impairment according to this study -- the first to evaluate cognitive impairment in children age three to six.

A recent study has shown that cognitive impairment is evident early on in preschool children with epilepsy, consistent with results of similar studies in older children. Age of onset of first seizure is a significant predictor of cognitive impairment according to this study -- the first to evaluate cognitive impairment in children age three to six. The report is available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE).

Epilepsy is characterized by recurrent seizures that range from mild staring spells to major convulsions, and frequently develops in early childhood. Studies have found that in the U.S. alone there are more than 325,000 children under the age of 15 who are diagnosed with epilepsy, with 45,000 new cases diagnosed each year. Medical evidence further suggests that early onset of seizures is a significant factor contributing to cognitive impairment in children.

For the present study, researchers reviewed medical data and psychological evaluations for 64 preschool children (3 to 6.11 years old) with active epilepsy in order to determine the frequency of cognitive impairment and the epilepsy-related factors contributing to the impairment. Children in the study group had a mean age of five, with seizure onset between 0 and 75 months. "Our study is the first to examine cognitive performance in preschool children with epilepsy," said lead researcher Kati Rantanen, a PhD candidate at the University of Tampere in Finland.

The study showed that the prevalence of epilepsy was roughly 3 per 1,000 children, which is consistent with prior studies in Finland and other developed countries. The team identified 27 children with focal seizures, 31 with generalized seizures, and 6 with unclassified seizure types. More than half of the children (64%) were receiving monotherapy of an anti-epileptic drug for seizure control. The seizures were well-controlled in 37% of children, partially controlled in 16%, and poorly controlled in the remaining 47% of participants.

Researchers determined cognitive function based on psychological evaluation, parental reports, and observations from daycare. The intelligence quotient (IQ) was used to measure cognitive function; children were classified as having normal IQ (IQ over 70) or with mild (50-69), moderate (35-49), or profound (less than 34) intellectual disability. In the preschool cohort, 50% of the children displayed normal cognitive function, 22% had mild cognitive impairment, and 28% showed moderate to severe intellectual disability.

The study found that early onset epilepsy is a risk factor for cognitive impairment. The authors caution that lower (IQ) test scores in young children with epilepsy may be partly a reflection of development delay rather than mental disability. "Early intervention programs may help to improve cognitive and psychological outcomes in preschoolers with epilepsy," Rantanen concluded. "Further prospective research is needed to explore the developmental course of children with epilepsy."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kati Rantanen, Kai Eriksson, Pirkko Nieminen. Cognitive impairment in preschool children with epilepsy. Epilepsia, 2011; DOI: 10.1111/j.1528-1167.2011.03092.x

Cite This Page:

Wiley-Blackwell. "Cognitive impairment seen in preschool children with epilepsy, study finds." ScienceDaily. ScienceDaily, 3 June 2011. <www.sciencedaily.com/releases/2011/06/110602095420.htm>.
Wiley-Blackwell. (2011, June 3). Cognitive impairment seen in preschool children with epilepsy, study finds. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2011/06/110602095420.htm
Wiley-Blackwell. "Cognitive impairment seen in preschool children with epilepsy, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/06/110602095420.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins