Featured Research

from universities, journals, and other organizations

Obesity raises breast cancer survivors' risk of dying of the cancer, study finds

Date:
June 6, 2011
Source:
The Endocrine Society
Summary:
Women with a healthy body weight before and after diagnosis of breast cancer are more likely to survive the disease long term, a new study finds.

Women with a healthy body weight before and after diagnosis of breast cancer are more likely to survive the disease long term, a new study finds.

The results were presented at The Endocrine Society's 93rd Annual Meeting in Boston.

The study, conducted in nearly 4,000 breast cancer survivors, found that obesity is strongly linked to death due to breast cancer. In particular, overweight or obese women with a history of estrogen receptor-positive breast cancer, but not those with estrogen receptor-negative cancer, had a higher risk of dying of their disease, said the study's lead author, Christina Dieli-Conwright, PhD.

"This relationship between dying and being obese or overweight may depend on whether the type of breast cancer is hormonally dependent," said Dieli-Conwright, assistant research professor at City of Hope National Medical Center in Duarte, Calif.

The research involved participants of the large California Teachers Study who, between 1995 and 2006, received a diagnosis of invasive breast cancer -- cancer that has spread beyond the breast ducts. Of the 3,995 women studied, 262 died of breast cancer through 2007, the authors reported in their abstract.

They defined obesity as a body mass index (BMI, in kg/m2) of 30 or higher. The authors obtained BMI, a measure of height and weight, from questionnaires showing each participant's self-reported height and weight at baseline and at age 18. Baseline was the beginning of the study and was near, but necessarily at, diagnosis, according to Dieli-Conwright.

Women who were obese at baseline had a 69 percent higher risk of dying of their breast cancer than did nonobese women, Dieli-Conwright said. This same increased mortality, or death, risk was present in women who were overweight (BMI of 25 to 29) at age 18.

The researchers also analyzed the mortality risk by estrogen receptor status (whether the hormone estrogen fuels the breast cancer). They found that the higher the BMI, the greater the risk of dying of breast cancer for women with estrogen-dependent cancer. They saw no such link in women with estrogen-negative breast cancer. Women who are obese or overweight tend to have higher levels of circulating estrogen, which likely explains this difference, Dieli-Conwright said.

Their findings add to the growing scientific evidence that obesity raises the risk of both developing breast cancer and dying of it.

"What we know now is that there is a strong link between dying from breast cancer and being obese," Dieli-Conwright said. "And it's not just your BMI near the time you're diagnosed that's important."

She continued, "With the obesity epidemic on the rise, weight management programs using exercise and diet are vital in cancer prevention and survivorship."

The National Cancer Institute and the California Breast Cancer Research Fund supported this study.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

The Endocrine Society. "Obesity raises breast cancer survivors' risk of dying of the cancer, study finds." ScienceDaily. ScienceDaily, 6 June 2011. <www.sciencedaily.com/releases/2011/06/110604182014.htm>.
The Endocrine Society. (2011, June 6). Obesity raises breast cancer survivors' risk of dying of the cancer, study finds. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2011/06/110604182014.htm
The Endocrine Society. "Obesity raises breast cancer survivors' risk of dying of the cancer, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/06/110604182014.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins