Featured Research

from universities, journals, and other organizations

Elderly Dutch lung patients' survival improved by new treatment options between 2003-2009

Date:
July 6, 2011
Source:
International Association for the Study of Lung Cancer
Summary:
New developments such as stereotactic ablative radiotherapy and improvements in surgical care in early-stage lung cancer have led to large survival gains for elderly Dutch patients, according to a population-based study.

New developments such as stereotactic ablative radiotherapy and improvements in surgical care in early-stage lung cancer have led to large survival gains for elderly Dutch patients, according to a population-based study presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer (IASLC).

Related Articles


The median survival for Dutch non-small cell lung cancer (NSCLC) patients increased by nearly 8 months between 2003 and 2009, following the advent of stereotactic ablative radiotherapy.

"In fit patients, surgery is accepted as the standard of care in an early-stage lung cancer, with radiation therapy widely considered a second choice," said Dr. Suresh Senan of VU University Medical Center in Amsterdam, one of the investigators.

However, only about one in every three patients aged 75 years and older is fit to undergo surgery. Until about 2003, up to 40 percent of elderly Dutch patients were left untreated because the second choice, conventional radiation -- which takes approximately 6-7 weeks to deliver and is associated with high recurrence rates -- was considered unattractive, Dr. Senan said.

Stereotactic ablative radiotherapy (SABR) was introduced in the Netherlands in 2003 and rapidly became the standard of care for peripheral stage I lung tumors measuring up to about 6 cm. SABR is a form of high-precision radiotherapy, characterized by the use of very high biological doses of radiation delivered in between 3 and 8 fractions in a 2-3 week period as an outpatient procedure.

Using data from the Netherlands Cancer Registry (NCR), researchers determined that the median survival of all elderly Dutch NSCLC patients increased to 24.4 months from 16.4 months between 2001 and 2009.

Radiotherapy utilization increased to 37.7% from 31.2%, and the corresponding median survival for patients treated with radiation increased by nearly 10 months, to 26.1 months from 16.8 months. No significant change in survival was seen in the group of patients that received no treatment.

"Patients who are aged 75 years and older, and who are fit to undergo surgery, should also be informed about a second curative modality of SABR, and about the differences in mortality and complications between these two treatments," Dr. Senan said. "Participation in the ongoing prospective clinical trials comparing surgery and SABR in fitter patient populations should be strongly encouraged."


Story Source:

The above story is based on materials provided by International Association for the Study of Lung Cancer. Note: Materials may be edited for content and length.


Cite This Page:

International Association for the Study of Lung Cancer. "Elderly Dutch lung patients' survival improved by new treatment options between 2003-2009." ScienceDaily. ScienceDaily, 6 July 2011. <www.sciencedaily.com/releases/2011/07/110706093702.htm>.
International Association for the Study of Lung Cancer. (2011, July 6). Elderly Dutch lung patients' survival improved by new treatment options between 2003-2009. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2011/07/110706093702.htm
International Association for the Study of Lung Cancer. "Elderly Dutch lung patients' survival improved by new treatment options between 2003-2009." ScienceDaily. www.sciencedaily.com/releases/2011/07/110706093702.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins