Featured Research

from universities, journals, and other organizations

Scientists connect gene to Alzheimer’s precondition

Date:
July 27, 2011
Source:
Cornell University
Summary:
Connecting a human gene to the risk of developing the Alzheimer's precondition known as mild cognitive impairment has been somewhat of a holy grail for scientists, but now a team of scientists has ended the quest.

Connecting a human gene to the risk of developing the Alzheimer's precondition known as Mild Cognitive Impairment has been somewhat of a holy grail for scientists, but a team led by researchers from Cornell University has ended the quest.

Related Articles


"We're excited about these findings because they help identify the segment of the population who will most benefit from effective treatments to prevent Alzheimer's type dementia," said Charles Brainerd, Cornell professor of Human Development in the College of Human Ecology and co-lead author of the study "Is Apolipoprotein E Genotype a Biomarker for Mild Cognitive Impairment? Findings From a Nationally Representative Study," which was published online this month by the journal Neuropsychology.

Previous research had identified e4 allele of the Apolipoprotein E genotype with the Alzheimer's precondition, but scientists had been unable to examine the gene using data that is both statistically significant and reliable. Brainerd, along with co-author Valerie Reyna, Cornell professor of human development, and researchers from the Mayo Clinic in Rochester, Minn., assembled large data sets from multiple institutions that more accurately represent older adults from all regions, racial groups and ethnic groups in the United States.

Classifying subtypes of Mild Cognitive Impairment was also critical to the study's success. The study outlines how new criteria for different impairment subtypes helped control the errors that plagued previous studies attempting to identify a link between the e4 allele and the Alzheimer's precondition.

"Knowing whether or not you're an e4 carrier, much like knowing whether you carry genetic markers for breast cancer, allows you to make life style choices that will minimize later risks of impairment. Smoking, alcohol and secondary diabetes are all associated with earlier transitions to Mild Cognitive Impairment and Alzheimer's," said Brainerd, who adds the findings will also help advance research in the field, as e4 carriers are prime research subjects.

The study was supported by a grant from the National Institutes of Health.


Story Source:

The above story is based on materials provided by Cornell University. Note: Materials may be edited for content and length.


Cite This Page:

Cornell University. "Scientists connect gene to Alzheimer’s precondition." ScienceDaily. ScienceDaily, 27 July 2011. <www.sciencedaily.com/releases/2011/07/110718142508.htm>.
Cornell University. (2011, July 27). Scientists connect gene to Alzheimer’s precondition. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2011/07/110718142508.htm
Cornell University. "Scientists connect gene to Alzheimer’s precondition." ScienceDaily. www.sciencedaily.com/releases/2011/07/110718142508.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Technology Is Ruining Snow Days For Students

How Technology Is Ruining Snow Days For Students

Newsy (Jan. 25, 2015) — More schools are using online classes to keep from losing time to snow days, but it only works if students have Internet access at home. Video provided by Newsy
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) — A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Amazing Technology Allows Blind Mother to See Her Newborn Son

Amazing Technology Allows Blind Mother to See Her Newborn Son

RightThisMinute (Jan. 23, 2015) — Not only is Kathy seeing her newborn son for the first time, but this is actually the first time she has ever seen a baby. Kathy and her sister, Yvonne, have been legally blind since childhood, but thanks to an amazing new technology, eSight glasses, which gives those who are legally blind the ability to see, she got the chance to see the birth of her son. It&apos;s an incredible moment and an even better story. Video provided by RightThisMinute
Powered by NewsLook.com
One Dose, Then Surgery to Test Tumor Drugs Fast

One Dose, Then Surgery to Test Tumor Drugs Fast

AP (Jan. 23, 2015) — A Phoenix hospital is experimenting with a faster way to test much needed medications for deadly brain tumors. Patients get a single dose of a potential drug, and hours later have their tumor removed to see if the drug had any affect. (Jan. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins