Featured Research

from universities, journals, and other organizations

New brain tumor gene identified for meningiomas

Date:
August 8, 2011
Source:
Expertanswer (Expertsvar in Swedish)
Summary:
The causes of brain tumors have been hard to discern in most cases. But researchers have previously identified an inherited predisposition for brain tumors. Now, in an international collaboration, they have also discovered a genetic variation that increases the risk of a certain type of brain tumor, called meningiomas.

The causes of brain tumours have been hard to discern in most cases. But Umeå University researchers in Sweden and their colleagues have previously identified an inherited predisposition for brain tumours. Now, in an international collaboration, they have also discovered a genetic variation that increases the risk of a certain type of brain tumour, called meningiomas.

Approximately 1,400 people are affected annually by tumours of the brain in Sweden and twenty per cent of those are afflicted with meningioma. The tumour itself is usually benign, but it can cause severe symptoms owing to of its location and because it is sometimes malignant. It arises from the meninges, and it is more common among women.

The study included samples from a total of 1,633 patients with meningiomas in Sweden, Germany, England, and Denmark. The results were published July 31 in the journal Nature Genetics.

The gene variant is close to MLLT10 on chromosome 10, a gene known to be involved in hematologic tumours. This gene has not previously been linked to increased risk of tumours.

"With more research we will be able to examine the function of these variants and whether they correlate with environmental factors, such as ionizing radiation, since the only environmental factor known previously for meningiomas is higher doses of ionizing radiation," says Beatrice Melin.

Co-authors of the study at Umeå University are researchers Beatrice Melin, Ulrika Andersson, Roger Henriksson, and Thomas Brännström.


Story Source:

The above story is based on materials provided by Expertanswer (Expertsvar in Swedish). Note: Materials may be edited for content and length.


Journal Reference:

  1. Sara E Dobbins, Peter Broderick, Beatrice Melin, Maria Feychting, Christoffer Johansen, Ulrika Andersson, Thomas Brännström, Johannes Schramm, Bianca Olver, Amy Lloyd, Yussanne P Ma, Fay J Hosking, Stefan Lönn, Anders Ahlbom, Roger Henriksson, Minouk J Schoemaker, Sarah J Hepworth, Per Hoffmann, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Lewin Eisele, Michael Kosteljanetz, Kenneth Muir, Anthony Swerdlow, Matthias Simon, Richard S Houlston. Common variation at 10p12.31 near MLLT10 influences meningioma risk. Nature Genetics, 2011; DOI: 10.1038/ng.879

Cite This Page:

Expertanswer (Expertsvar in Swedish). "New brain tumor gene identified for meningiomas." ScienceDaily. ScienceDaily, 8 August 2011. <www.sciencedaily.com/releases/2011/08/110808105953.htm>.
Expertanswer (Expertsvar in Swedish). (2011, August 8). New brain tumor gene identified for meningiomas. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2011/08/110808105953.htm
Expertanswer (Expertsvar in Swedish). "New brain tumor gene identified for meningiomas." ScienceDaily. www.sciencedaily.com/releases/2011/08/110808105953.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) — The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) — Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins