Featured Research

from universities, journals, and other organizations

Improved chances for breast preservation in cases of lobular breast cancer

Date:
August 26, 2011
Source:
Medical University of Vienna
Summary:
Researchers in Austria have found that the breast of one in two women with lobular breast cancer can be preserved through chemotherapy prior to a breast operation.

Researchers at the Medical University of Vienna have found that the breast of one in two women with lobular breast cancer can be preserved through chemotherapy prior to a breast operation.

Related Articles


"Up until now it had been the view that neoadjuvant chemotherapy hardly had any benefits in cases of lobular breast cancer due to the poor response rate of the cancer, however no one had yet examined the question of the breast preservation rate," says study leader Prof. Dr. Florian Fitzal from the University Department of Surgery, who also works at MedUni Vienna's interdisciplinary Breast Centre. "We were able to show that one in two women, who has this type of breast cancer and would really need complete removal of the breast, can keep the breast with the help of this treatment strategy.

The treatment is principally responsible for a sufficient reduction in size of the cancer, so that during the subsequent surgical excision, the breast could be then preserved in 48 percent of cases. The medium-term oncological certainty of breast preservation is also shown in this case. Only three percent have a local recurrence after five years, i.e. a tumour found at the same site. Therefore we should not rule out a priori neoadjuvant chemotherapy in cases of lobular breast cancer."

The effect is a marked improvement of the patient's quality of life. Fitzal says, "That was and still is our aim. We wanted to achieve this through the combination of the neoadjuvant therapy with the oncoplastic surgical methods, which are provided here in Vienna. We hope that anti-hormonal therapy prior to surgery will bring even further improvements." The study's results have now been published in the American specialist publication Annals of Surgical Oncology.

Approximately every fifth patient suffers from lobular breast cancer, which is a less aggressive form than the more frequent ductal carcinoma. However, lobular breast cancer generally has more branches and the tumour is generally larger in terms of its diameter. Nodules are only palpable later in cases of lobular breast cancer. The consequence of this particular type of spreading is that the tumour is frequently only discovered when it is already at a locally advanced stage.


Story Source:

The above story is based on materials provided by Medical University of Vienna. Note: Materials may be edited for content and length.


Journal Reference:

  1. Florian Fitzal, Martina Mittlboeck, Guenther Steger, Rupert Bartsch, Margaretha Rudas, Peter Dubsky, Otto Riedl, Raimund Jakesz, Michael Gnant. Neoadjuvant Chemotherapy Increases the Conservation in Lobular-Type Breast Cancer. Annals of Surgical Oncology, 2011; [link]

Cite This Page:

Medical University of Vienna. "Improved chances for breast preservation in cases of lobular breast cancer." ScienceDaily. ScienceDaily, 26 August 2011. <www.sciencedaily.com/releases/2011/08/110826085144.htm>.
Medical University of Vienna. (2011, August 26). Improved chances for breast preservation in cases of lobular breast cancer. ScienceDaily. Retrieved April 1, 2015 from www.sciencedaily.com/releases/2011/08/110826085144.htm
Medical University of Vienna. "Improved chances for breast preservation in cases of lobular breast cancer." ScienceDaily. www.sciencedaily.com/releases/2011/08/110826085144.htm (accessed April 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, April 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

7-Year-Old Girl Gets 3-D Printed 'robohand'

7-Year-Old Girl Gets 3-D Printed 'robohand'

AP (Mar. 31, 2015) — Although she never had much interest in prosthetic limbs before, Faith Lennox couldn&apos;t wait to slip on her new robohand. The 7-year-old, who lost part of her left arm when she was a baby, grabbed it as soon as it came off a 3-D printer. (March 31) Video provided by AP
Powered by NewsLook.com
Solitair Device Aims to Takes Guesswork out of Sun Safety

Solitair Device Aims to Takes Guesswork out of Sun Safety

Reuters - Innovations Video Online (Mar. 31, 2015) — The Solitair device aims to take the confusion out of how much sunlight we should expose our skin to. Small enough to be worn as a tie or hair clip, it monitors the user&apos;s sun exposure by taking into account their skin pigment, location and schedule. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins