Featured Research

from universities, journals, and other organizations

Cough may warn of danger for patients with lung-scarring disease

Date:
October 18, 2011
Source:
Wiley-Blackwell
Summary:
A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

When idiopathic pulmonary fibrosis develops, tissue deep in the lungs becomes thick and scarred, likely due to a response to an unknown substance. The condition affects approximately 100,000 individuals in the United States, and up to half die within three years of being diagnosed.

Almost all patients with idiopathic pulmonary fibrosis experience shortness of breath. The second most common symptom is cough. Shortness of breath is a known warning sign that a patient has a serious form of the disease, but little is known about the importance of cough.To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

The authors concluded that patients with idiopathic pulmonary fibrosis who cough may have a worse prognosis compared with patients who do not cough. While additional studies are needed to validate the results, patients who cough may benefit from closer monitoring and more aggressive treatments.

"These findings improve our understanding of cough in idiopathic pulmonary fibrosis," said Dr. Ryerson. "The reason for the association between cough and never having smoked is unknown, but may provide insight into the pathogenesis of cough in idiopathic pulmonary fibrosis and thus prompt future research in this area," he added.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Christopher J. Ryerson, Marta Abbritti, Brett Ley, Brett M. Elicker, Kirk D. Jones, Harold R. Collard. Cough predicts prognosis in idiopathic pulmonary fibrosis. Respirology, 2011; 16 (6): 969 DOI: 10.1111/j.1440-1843.2011.01996.x

Cite This Page:

Wiley-Blackwell. "Cough may warn of danger for patients with lung-scarring disease." ScienceDaily. ScienceDaily, 18 October 2011. <www.sciencedaily.com/releases/2011/10/111018121851.htm>.
Wiley-Blackwell. (2011, October 18). Cough may warn of danger for patients with lung-scarring disease. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2011/10/111018121851.htm
Wiley-Blackwell. "Cough may warn of danger for patients with lung-scarring disease." ScienceDaily. www.sciencedaily.com/releases/2011/10/111018121851.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins