Featured Research

from universities, journals, and other organizations

One size does not fit all for knee replacements and other medical devices, expert says

Date:
October 20, 2011
Source:
Yale University
Summary:
Undergoing a knee replacement involves sophisticated medical equipment, but innovative prosthetic design may not offer the same benefits for all knee replacement recipients, researchers report.

Undergoing a knee replacement involves sophisticated medical equipment, but innovative prosthetic design may not offer the same benefits for all knee replacement recipients, Yale School of Medicine researchers report in a perspective article in the Oct. 20 issue of the New England Journal of Medicine.

Devices like pacemakers, artificial joints, and defibrillators have extended lives and improved the quality of life for countless people. Medical device manufacturing has turned into a multi-billion dollar industry, with the United States spending an estimated $95 billion on these devices last year alone, according to the article, which also noted that oversight of device innovation is under scrutiny for safety issues.

The current expedited approval process for low-risk medical devices is based on claims of similarity to previously approved devices, and as such may encourage development of devices that provide only small improvements at higher cost than their predecessors, note the researchers.

To assess whether the addition of a new medical devices to market would yield a greater benefit than using an older version, first author Dr. Lisa G. Suter, assistant professor of internal medicine at Yale School of Medicine, and colleagues used a mathematical model to simulate the consequences of undergoing total knee replacement for end-stage knee osteoarthritis with both standard and innovative implants. Knee osteoarthritis is a frequent and costly cause of disability in the United States.

The researchers used the Osteoarthritis Policy Model, a validated computer simulation model of knee osteoarthritis natural history and management, to project life expectancy and implant survival associated with using standard and innovative implants for both young and older total knee replacement recipients with and without illness.

Suter and her team found that older patients or those with multiple co-existing conditions may not live long enough to benefit from small, incremental gains in the durability of the implant.

"Patients, physicians, device manufacturers, and policymakers should be aware that innovative medical devices may not offer equal value in all patients," said Suter, who added that mathematical models may improve medical device development, evaluation and monitoring.

Other authors on the perspective article include A. David Paltiel, Benjamin N. Rome, Daniel H. Solomon, M.D., Ilya Golovaty, Hanna Gerlovin, Jeffrey N. Katz, M.D., and Elena Losina, from Brigham and Women's Hospital and Harvard Medical School.


Story Source:

The above story is based on materials provided by Yale University. The original article was written by Karen N. Peart. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lisa G. Suter, A. David Paltiel, Benjamin N. Rome, Daniel H. Solomon, Ilya Golovaty, Hanna Gerlovin, Jeffrey N. Katz, Elena Losina. Medical Device Innovation — Is “Better” Good Enough? New England Journal of Medicine, 2011; 365 (16): 1464 DOI: 10.1056/NEJMp1109285

Cite This Page:

Yale University. "One size does not fit all for knee replacements and other medical devices, expert says." ScienceDaily. ScienceDaily, 20 October 2011. <www.sciencedaily.com/releases/2011/10/111019205622.htm>.
Yale University. (2011, October 20). One size does not fit all for knee replacements and other medical devices, expert says. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2011/10/111019205622.htm
Yale University. "One size does not fit all for knee replacements and other medical devices, expert says." ScienceDaily. www.sciencedaily.com/releases/2011/10/111019205622.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins