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New weapon against cancer: Microwaves can be used to create medical images

Date:
October 26, 2011
Source:
Chalmers University of Technology
Summary:
A research team from Sweden has developed new techniques of cancer diagnosis and treatment with the aid of microwaves, which could play a pioneering role in the battle against cancer. These techniques could save many lives and are more effective, less invasive and simpler than currently available alternatives. Clinical studies are now being planned.

The “microwave tomograph” currently consists of some thirty antennas arranged around a cylindrical container adapted to the breast. All antennas act both as transmitters and receivers. The microwaves spread out in a complex pattern that is analyzed by advanced algorithms, which reconstruct an image of the breast tissue in 3-D.
Credit: Jan-Olof Yxell/Chalmers

A research team from Chalmers University of Technology has developed new techniques of cancer diagnosis and treatment with the aid of microwaves, which could play a pioneering role in the battle against cancer. These techniques could save many lives and are more effective, less invasive and simpler than currently available alternatives. Clinical studies are now being planned.

The Chalmers team expects to be able to test two different techniques on patients within the next six months. One method is an alternative to mammography, i.e. using X-rays to detect breast cancer. The other aims to treat tumours in the head and neck by heating the cancer cells.

Microwaves can be used to create medical images -- a new technique known as microwave tomography. Andreas Fhager, Associate Professor of Biomedical Electromagnetics, has developed a system to detect breast cancer with the new technique. He points out that the method has several advantages over mammography.

"We obtain three-dimensional images showing significantly better contrast between healthy and malignant tissue compared to X-rays. That makes it easier to detect even really small tumours that may currently be obscured by healthy tissue, thus creating the preconditions for much more reliable diagnosis."

"Unlike X-rays, the technique also emits negligible doses of non-ionising radiation -- less than a hundredth of the radiation to which you are exposed when talking on a mobile phone."

The idea is to use the technique in conjunction with a treatment couch, equipped with holes for the breasts, to which the thirty or so antennas required by the examination are connected. It should be considerably more comfortable for patients than mammography. The method is also much less expensive, not only because microwave equipment is not so costly, but also because the clearer images make interpretation easier for the doctors.

In the second Chalmers project, the microwaves are actually used to destroy the tumours by heating them, a process known as hyperthermia. Clinical studies have shown that treatment with conventional radiotherapy and chemotherapy in combination with hyperthermia may double the long-term ability to cure certain forms of cancer, such as cervical cancer and soft-tissue sarcoma.

"We are now developing a new hyperthermia system that can reach deep-seated tumours in the head and neck with high accuracy," says Hana Dobšνček Trefnα, a PhD in Biomedical Engineering. "In this way, higher temperatures can be reached in the tumour without affecting the surrounding tissue."

With time, the Chalmers team hope to be able to combine both methods. As soon as a tumour is detected, the already connected antennas could be used to start treating the tumour directly while at the same time monitoring that the right tissue is heated up. The method should also be applicable for other parts of the body than breasts, head and neck.

Theranostics -- the treatment and diagnosis of diseases in a single system -- is a growing area of research, and the Chalmers team believe that microwaves have great potential in the field. The underlying microwave technology is already being used in the "Strokefinder," a helmet that can distinguish between blood clots and bleeding in the brain. The Strokefinder is currently undergoing clinical trials at Sahlgrenska Hospital.


Story Source:

The above story is based on materials provided by Chalmers University of Technology. Note: Materials may be edited for content and length.


Cite This Page:

Chalmers University of Technology. "New weapon against cancer: Microwaves can be used to create medical images." ScienceDaily. ScienceDaily, 26 October 2011. <www.sciencedaily.com/releases/2011/10/111025090349.htm>.
Chalmers University of Technology. (2011, October 26). New weapon against cancer: Microwaves can be used to create medical images. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2011/10/111025090349.htm
Chalmers University of Technology. "New weapon against cancer: Microwaves can be used to create medical images." ScienceDaily. www.sciencedaily.com/releases/2011/10/111025090349.htm (accessed September 1, 2014).

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