Featured Research

from universities, journals, and other organizations

Environmental exposure to organochlorines may impact male reproduction

Date:
January 19, 2012
Source:
George Washington University Medical Center
Summary:
Environmental exposure to organochlorine chemicals, including polychlorinated biphenyls (PCBs) and p,p'-DDE (the main metabolite of the insecticide DDT) can affect male reproduction, according to new research.

Melissa Perry, Sc.D., M.H.S., professor and chair of the Department of Environmental and Occupational Health at the GW School of Public Health and Health Services and adjunct associate professor at the Harvard School of Public Health, led an observational study indicating that environmental exposure to organochlorine chemicals, including Polychlorinated Biphenyls (PCBs) and p,p'-DDE (the main metabolite of the insecticide DDT) can affect male reproduction.

Related Articles


The research was published online on Dec. 21, 2011 in the journal Environmental Health Perspectives.

The researchers studied 192 men who were part of couples that were sub-fertile, to see if the men with higher levels of organochlorines in their blood showed evidence of increased rates of sperm abnormalities. They looked for sperm disomy, which occurs when sperm cells have an abnormal number of chromosomes. While all men have a certain number of sperm with such abnormalities, researchers found that men with higher levels of DDE and PCBs had significantly higher rates of sperm abnormalities.

"This research adds to the already existing body of evidence suggesting that environmental exposure to certain chemicals can affect male fertility and reproduction. We need to further understand the mechanisms through which these chemicals impact sperm," said Dr. Perry. "While we cannot avoid chemicals that already persist in the environment, it is imperative that decisions about putting biologically active chemicals into the environment need to be made very carefully, because there can be unanticipated consequences down the road."

The researchers used a new sperm imaging methodology developed by Dr. Perry and colleagues to detect the chromosomal abnormalities, which allowed them to study a larger sampling of individuals than previous studies.


Story Source:

The above story is based on materials provided by George Washington University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Megan E. McAuliffe, Paige L. Williams, Susan A. Korrick, Larisa M. Altshul, Melissa J. Perry. Environmental Exposure to Polychlorinated Biphenyls and p,p’-DDE and Sperm Sex Chromosome Disomy. Environmental Health Perspectives, 2011; DOI: 10.1289/ehp.1104017

Cite This Page:

George Washington University Medical Center. "Environmental exposure to organochlorines may impact male reproduction." ScienceDaily. ScienceDaily, 19 January 2012. <www.sciencedaily.com/releases/2012/01/120109145901.htm>.
George Washington University Medical Center. (2012, January 19). Environmental exposure to organochlorines may impact male reproduction. ScienceDaily. Retrieved January 30, 2015 from www.sciencedaily.com/releases/2012/01/120109145901.htm
George Washington University Medical Center. "Environmental exposure to organochlorines may impact male reproduction." ScienceDaily. www.sciencedaily.com/releases/2012/01/120109145901.htm (accessed January 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, January 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins