Featured Research

from universities, journals, and other organizations

Diabetes drug can prevent heart disease, new study suggests

Date:
March 25, 2012
Source:
University of Gothenburg
Summary:
The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study.

The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study conducted at the Sahlgrenska Academy, at the University of Gothenburg, Sweden.

Related Articles


Researchers at the University of Gothenburg's Sahlgrenska Academy have shown in a preliminary study in rats that one of the most common diabetes drugs, metformin, also has a protective effect on the heart.

The study, carried out in collaboration with a research group from Naples and published in the journal Diabetes, reveals that metformin helps increase pumping capacity, improve energy balance, reduce the accumulation of fat, and limit the loss of heart cells through programmed cell death.

Long term effect

The results were compared with animals treated with another diabetes drug, which proved to have no positive effects on the heart.

“The animals in our study were treated with metformin for a whole year, so the effect seems to persist,” says Jφrgen Isgaard, the researcher at the Sahlgrenska Academy who led the Swedish research group involved in the study.

New study on patients

Diabetes drugs have proved to have a number of serious side-effects for people with heart disease. Rosiglitazone, for example, was recently withdrawn due to its cardiac side-effects. Metformin too can occasionally have side-effects, primarily in patients with kidney failure.

“Our results nevertheless strengthen the indication for metformin as a diabetes medicine, and we hope that they are now followed up with studies on actual patients,” says Isgaard.

The article Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model was published in Diabetes on 22 February.


Story Source:

The above story is based on materials provided by University of Gothenburg. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. Cittadini, R. Napoli, M. G. Monti, D. Rea, S. Longobardi, P. A. Netti, M. Walser, M. Sama, G. Aimaretti, J. Isgaard, L. Sacca. Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model. Diabetes, 2012; 61 (4): 944 DOI: 10.2337/db11-1132

Cite This Page:

University of Gothenburg. "Diabetes drug can prevent heart disease, new study suggests." ScienceDaily. ScienceDaily, 25 March 2012. <www.sciencedaily.com/releases/2012/03/120325102605.htm>.
University of Gothenburg. (2012, March 25). Diabetes drug can prevent heart disease, new study suggests. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2012/03/120325102605.htm
University of Gothenburg. "Diabetes drug can prevent heart disease, new study suggests." ScienceDaily. www.sciencedaily.com/releases/2012/03/120325102605.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) — An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins