Featured Research

from universities, journals, and other organizations

Diabetes drug can prevent heart disease, new study suggests

Date:
March 25, 2012
Source:
University of Gothenburg
Summary:
The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study.

The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study conducted at the Sahlgrenska Academy, at the University of Gothenburg, Sweden.

Researchers at the University of Gothenburg's Sahlgrenska Academy have shown in a preliminary study in rats that one of the most common diabetes drugs, metformin, also has a protective effect on the heart.

The study, carried out in collaboration with a research group from Naples and published in the journal Diabetes, reveals that metformin helps increase pumping capacity, improve energy balance, reduce the accumulation of fat, and limit the loss of heart cells through programmed cell death.

Long term effect

The results were compared with animals treated with another diabetes drug, which proved to have no positive effects on the heart.

“The animals in our study were treated with metformin for a whole year, so the effect seems to persist,” says Jφrgen Isgaard, the researcher at the Sahlgrenska Academy who led the Swedish research group involved in the study.

New study on patients

Diabetes drugs have proved to have a number of serious side-effects for people with heart disease. Rosiglitazone, for example, was recently withdrawn due to its cardiac side-effects. Metformin too can occasionally have side-effects, primarily in patients with kidney failure.

“Our results nevertheless strengthen the indication for metformin as a diabetes medicine, and we hope that they are now followed up with studies on actual patients,” says Isgaard.

The article Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model was published in Diabetes on 22 February.


Story Source:

The above story is based on materials provided by University of Gothenburg. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. Cittadini, R. Napoli, M. G. Monti, D. Rea, S. Longobardi, P. A. Netti, M. Walser, M. Sama, G. Aimaretti, J. Isgaard, L. Sacca. Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model. Diabetes, 2012; 61 (4): 944 DOI: 10.2337/db11-1132

Cite This Page:

University of Gothenburg. "Diabetes drug can prevent heart disease, new study suggests." ScienceDaily. ScienceDaily, 25 March 2012. <www.sciencedaily.com/releases/2012/03/120325102605.htm>.
University of Gothenburg. (2012, March 25). Diabetes drug can prevent heart disease, new study suggests. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2012/03/120325102605.htm
University of Gothenburg. "Diabetes drug can prevent heart disease, new study suggests." ScienceDaily. www.sciencedaily.com/releases/2012/03/120325102605.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) — The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) — Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins