Featured Research

from universities, journals, and other organizations

Realizing the promise of RNA nanotechnology for new drug development

Date:
September 4, 2012
Source:
Mary Ann Liebert, Inc., Publishers
Summary:
The use of RNA in nanotechnology applications is highly promising for many applications, including the development of new therapeutic compounds. Key technical challenges remain, though, and the challenges and opportunities associated with the use of RNA molecules in nanotechnology approaches are presented in a review article.

The use of RNA in nanotechnology applications is highly promising for many applications, including the development of new therapeutic compounds. Key technical challenges remain, though, and the challenges and opportunities associated with the use of RNA molecules in nanotechnology approaches are presented in a review article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc.

Related Articles


Peixuan Guo and colleagues, University of Kentucky, Lexington, highlight the ability of RNA to self-assemble into nanoparticles with diverse structures. In "Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology," the authors provide a detailed description of the main challenges faced by the RNA therapeutics industry, including the chemical and thermodynamic instability of the molecules, potential safety and side effect issues, difficulties in delivery and specific targeting, and low yield and high production costs in manufacturing.

"The remarkable structural and enzymatic properties of RNA continue to astound us," says Executive Editor Fintan Steele, PhD, SomaLogic, Inc., Boulder, CO. "It is exciting to see those properties increasingly realized for the benefit of human health and welfare, as described by Dr. Guo and his colleagues."

Nucleic Acid Therapeutics is under the editorial leadership of Co-Editors-in-Chief Bruce A. Sullenger, PhD, Duke Translational Research Institute, Duke University Medical Center, Durham, NC, and C.A. Stein, MD, PhD, City of Hope National Medical Center, Duarte, CA; and Executive Editor Fintan Steele, PhD, SomaLogic, Boulder, CO.


Story Source:

The above story is based on materials provided by Mary Ann Liebert, Inc., Publishers. Note: Materials may be edited for content and length.


Journal Reference:

  1. Peixuan Guo, Farzin Haque, Brent Hallahan, Randall Reif, and Hui Li. Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology. Nucleic Acid Therapeutics, 2012, 22(4): 226-245 DOI: 10.1089/nat.2012.0350

Cite This Page:

Mary Ann Liebert, Inc., Publishers. "Realizing the promise of RNA nanotechnology for new drug development." ScienceDaily. ScienceDaily, 4 September 2012. <www.sciencedaily.com/releases/2012/09/120904144850.htm>.
Mary Ann Liebert, Inc., Publishers. (2012, September 4). Realizing the promise of RNA nanotechnology for new drug development. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2012/09/120904144850.htm
Mary Ann Liebert, Inc., Publishers. "Realizing the promise of RNA nanotechnology for new drug development." ScienceDaily. www.sciencedaily.com/releases/2012/09/120904144850.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Newsy (Nov. 23, 2014) Microsoft has robotic security guards working at its Silicon Valley Campus. Video provided by Newsy
Powered by NewsLook.com
Toyota's Hydrogen Fuel-Cell Green Car Soon Available in the US

Toyota's Hydrogen Fuel-Cell Green Car Soon Available in the US

AFP (Nov. 21, 2014) Toyota presented its hydrogen fuel-cell compact car called "Mirai" to US consumers at the Los Angeles auto show. The car should go on sale in 2015 for around $60.000. It combines stored hydrogen with oxygen to generate its own power. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
Google Announces Improvements To Balloon-Borne Wi-Fi Project

Google Announces Improvements To Balloon-Borne Wi-Fi Project

Newsy (Nov. 21, 2014) In a blog post, Google said its balloons have traveled 3 million kilometers since the start of Project Loon. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins