Featured Research

from universities, journals, and other organizations

Guys, take note: Male birth control pill may be ready soon

Date:
September 5, 2012
Source:
Texas A&M University
Summary:
Attention men: The day may be coming soon when you can take your own birth control pill with no side effects, according to a new study.

Attention men: The day may be coming soon when you can take your own birth control pill with no side effects, according to a study done by a group of scientists that includes a Texas A&M University researcher.

Related Articles


Qinglei Li, an assistant professor in Texas A&M's College of Veterinary Medicine & Biomedical Sciences, is part of a team of researchers led by Martin Matzuk at Baylor College of Medicine and James Bradner at Dana-Farber Cancer Institute who made the discovery, and their work is published in the journal Cell.

Working on mice, the team found that a compound called JQ1 acts as an inhibitor to sperm production and also sperm mobility.

"Both of these are needed for fertility, but JQ1 prevents both," Li says of the findings.

"It stopped the sperm production very dramatically. More good news is that there appear to be no side effects whatsoever. Once the JQ1 was no longer given to the mice, they were back to their normal reproduction rates, and it did not affect mating behavior or the health of the offspring."

Though the mice were given injections, the team believes that a pill could eventually be developed for the same results.

A male contraceptive pill has been talked about for decades, but so far none has been successfully created despite a strong demand.

While many men might be reluctant to take out the trash or ask for directions if they are lost, recent studies have shown that about 70 percent of men would be willing to take a birth control pill if it were available.

One drawback to many female contraceptives is that they sometimes interfere with hormones, especially estrogen. But Li says the team is confident that JQ1 does not affect testosterone levels in men, and appears to have no other side effects as well.

As with many discoveries, the JQ1 compound appears to have come about by accident.

It was originally used for anti-cancer treatments, but researchers found it was also an excellent compound in controlling fertility.

"This is an exciting step in male contraception," Li adds.

"A compound with more specificity will be needed before clinical trials can be done for humans. It does not mean a male birth control just yet, but it is a great step forward in that direction."


Story Source:

The above story is based on materials provided by Texas A&M University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Martin M. Matzuk, Michael R. McKeown, Panagis Filippakopoulos, Qinglei Li, Lang Ma, Julio E. Agno, Madeleine E. Lemieux, Sarah Picaud, Richard N. Yu, Jun Qi, Stefan Knapp, James E. Bradner. Small-Molecule Inhibition of BRDT for Male Contraception. Cell, 2012; 150 (4): 673 DOI: 10.1016/j.cell.2012.06.045

Cite This Page:

Texas A&M University. "Guys, take note: Male birth control pill may be ready soon." ScienceDaily. ScienceDaily, 5 September 2012. <www.sciencedaily.com/releases/2012/09/120905141916.htm>.
Texas A&M University. (2012, September 5). Guys, take note: Male birth control pill may be ready soon. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2012/09/120905141916.htm
Texas A&M University. "Guys, take note: Male birth control pill may be ready soon." ScienceDaily. www.sciencedaily.com/releases/2012/09/120905141916.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) — Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) — Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) — AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) — Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

More Coverage


Finally, the Promise of Male Birth Control in a Pill: Compound Makes Mice Reversibly Infertile

Aug. 16, 2012 — Researchers have finally found a compound that may offer the first effective and hormone-free birth control pill for men. The study shows that the small molecule makes male mice reversibly infertile ... read more

A Male Contraceptive Pill in the Making?

Aug. 16, 2012 — Researchers have used a small molecule compound to generate reversible birth control in male ... read more

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins