Featured Research

from universities, journals, and other organizations

Renal transplantation is best treatment option for improving quality of life in people with late-stage chronic kidney disease

Date:
September 11, 2012
Source:
Public Library of Science
Summary:
In people with late-stage chronic kidney disease, renal transplantation is the best treatment option to improve quality of life, but for those receiving dialysis, home-based automated peritoneal dialysis (in which fluids are infused into the abdominal cavity and can be done nightly at home) provides a better quality of life than continuous ambulatory peritoneal dialysis (a type of dialysis performed continuously throughout the day), according to a study by Australian researchers.

In people with late-stage chronic kidney disease, renal transplantation is the best treatment option to improve quality of life, but for those receiving dialysis, home-based automated peritoneal dialysis (in which fluids are infused into the abdominal cavity and can be done nightly at home) provides a better quality of life than continuous ambulatory peritoneal dialysis (a type of dialysis performed continuously throughout the day), according to a study by Australian researchers published in this week's PLoS Medicine.

Related Articles


The researchers, led by Melanie Wyld from the University of Sydney, reviewed and assimilated all of the available published evidence to investigate whether quality of life in people with late-stage chronic kidney disease (as measured by utilities -- a numerical value measured on a 0 to 1 scale [where 0 represents death and 1 represents full health] of the strength of an individual's preference for specified health-related outcomes) differed according to treatment type.

In their analysis, which represented over 56,000 patients, the researchers found that the average utility for those who had a renal transplantation was 0.82, followed by the pre-dialysis group (0.79), patients treated with dialysis (0.70), and finally, patients receiving conservative care (0.62). When comparing the type of dialysis, the researchers found that there was no significant difference in utilities between haemodialysis and peritoneal dialysis, but patients using automated peritoneal dialysis had, on average, a higher utility (0.80) than those treated with continuous ambulatory peritoneal dialysis (0.72).

In addition to helping to inform economic evaluations of treatment options, the information from this analysis can help guide clinicians caring for patients with chronic kidney disease in their discussions about possible treatment options.

The authors conclude: "Our results suggest that automated peritoneal dialysis, a home-based form of dialysis that accounts for just 7% of dialysis patients in the UK and 4% of dialysis patients in the United States, has a significantly higher mean utility than continuous ambulatory peritoneal dialysis."

Commenting on the findings, the authors said: "The finding that transplant patients' utilities increased significantly between the 1980s and the 2000s likely reflects improvements in transplant care and evolving clinical practice."

They add: "We found that patients who chose conservative care had significantly lower quality of life than patients treated with dialysis, although the number of studies was small."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Wyld M, Morton RL, Hayen A, Howard K, Webster AC. A Systematic Review and Meta-Analysis of Utility-Based Quality of Life in Chronic Kidney Disease Treatments. PLoS Medicine, 2012; 9 (9): e1001307 DOI: 10.1371/journal.pmed.1001307

Cite This Page:

Public Library of Science. "Renal transplantation is best treatment option for improving quality of life in people with late-stage chronic kidney disease." ScienceDaily. ScienceDaily, 11 September 2012. <www.sciencedaily.com/releases/2012/09/120911172300.htm>.
Public Library of Science. (2012, September 11). Renal transplantation is best treatment option for improving quality of life in people with late-stage chronic kidney disease. ScienceDaily. Retrieved April 25, 2015 from www.sciencedaily.com/releases/2012/09/120911172300.htm
Public Library of Science. "Renal transplantation is best treatment option for improving quality of life in people with late-stage chronic kidney disease." ScienceDaily. www.sciencedaily.com/releases/2012/09/120911172300.htm (accessed April 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

85 Killed in Niger by Meningitis Since Start of Year

85 Killed in Niger by Meningitis Since Start of Year

AFP (Apr. 24, 2015) A meningitis outbreak in Niger has killed 85 people since the start of the year prompting authorities to close schools in the capital Niamey until Monday. Video provided by AFP
Powered by NewsLook.com
C-Section Births a Trend in Brazil

C-Section Births a Trend in Brazil

AFP (Apr. 24, 2015) More than half of Brazil&apos;s babies are born via cesarean section, as mothers and doctors opt for a faster and less painful experience despite the health risks. Duration: 02:02 Video provided by AFP
Powered by NewsLook.com
Anti-Malaria Jab Hope

Anti-Malaria Jab Hope

Reuters - News Video Online (Apr. 24, 2015) The world&apos;s first anti-malaria vaccine could get the go-ahead for use in Africa from October if approved by international regulators. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
3D Food Printing: The Meal of the Future?

3D Food Printing: The Meal of the Future?

AP (Apr. 23, 2015) Developers of 3D food printing hope the culinary technology will revolutionize the way we cook and eat. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins