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Gingko biloba does not improve cognition in multiple sclerosis patients, study finds

Date:
September 14, 2012
Source:
Oregon Health & Science University
Summary:
Many people with multiple sclerosis for years have taken the natural supplement Gingko biloba, believing it helps them with cognitive problems associated with the disease. But the science now says otherwise. A new study says Gingko biloba does not improve cognitive performance in people with multiple sclerosis.

Many people with multiple sclerosis for years have taken the natural supplement Gingko biloba, believing it helps them with cognitive problems associated with the disease.

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But the science now says otherwise. A new study published in the journal Neurology says Gingko biloba does not improve cognitive performance in people with multiple sclerosis. The research was published in the Sept. 5, 2012, issue of Neurology, the medical journal of the American Academy of Neurology. The current study was a more extensive look at the question after a smaller 2005 pilot study suggested there might have been some cognitive benefits in MS patients using the supplement. That study found that Gingko seemed to improve attention in MS patients with cognitive impairment.

But the larger follow-up study, conducted with patients at the Portland and Seattle Veterans Affairs medical centers, found no cognitive benefits to using Gingko.

"It's important for scientists to continue to analyze what might help people with cognitive issues relating to their MS," said Jesus Lovera, M.D., the study's lead author, a former fellow at the Portland VA Medical Center and former instructor in Oregon Health & Science University's Department of Neurology, where he did much of the work on the study. Lovera is now with the Department of Neurology at the Louisiana State University Health Sciences Center.

"We wanted to follow up on the earlier findings that suggested there may be some benefit. But we believe this larger study settles the question: Gingko simply doesn't improve cognitive performance with MS patients," said Lovera.

About one-half of people with MS will develop cognitive problems, and those cognitive problems can be debilitating in some people, said Dennis Bourdette, M.D., a co-author of the study, co-director of the VA MS Center of Excellence-West at the Portland VA Medical Center and chairman of the OHSU Department of Neurology. The most common problems relate to memory, attention and concentration, and information processing.

There is no known treatment that can improve cognition with MS patients -- which is partly why MS patients and researchers had hoped that Gingko biloba could help.

Lovera was also the lead author in the 2005 study, conducted at OHSU. That study included 39 participants who were given Gingko biloba or a placebo. The new study included 120 participants given Gingko or a placebo.

The study was supported by a grant from the U.S. Department of Veterans Affairs Rehabilitation Research and Development Service.


Story Source:

The above story is based on materials provided by Oregon Health & Science University. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. F. Lovera, E. Kim, E. Heriza, M. Fitzpatrick, J. Hunziker, A. P. Turner, J. Adams, T. Stover, A. Sangeorzan, A. Sloan, D. Howieson, K. Wild, J. Haselkorn, D. Bourdette. Ginkgo biloba does not improve cognitive function in MS: A randomized placebo-controlled trial. Neurology, 2012; DOI: 10.1212/WNL.0b013e31826aac60

Cite This Page:

Oregon Health & Science University. "Gingko biloba does not improve cognition in multiple sclerosis patients, study finds." ScienceDaily. ScienceDaily, 14 September 2012. <www.sciencedaily.com/releases/2012/09/120914133137.htm>.
Oregon Health & Science University. (2012, September 14). Gingko biloba does not improve cognition in multiple sclerosis patients, study finds. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2012/09/120914133137.htm
Oregon Health & Science University. "Gingko biloba does not improve cognition in multiple sclerosis patients, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/09/120914133137.htm (accessed November 26, 2014).

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Ginkgo Biloba Doesn’t Improve Cognitive Function in Multiple Sclerosis, Research Finds

Sep. 11, 2012 — A new study has found that the herbal supplement Ginkgo biloba does not improve cognitive function in patients with multiple sclerosis. Cognitive impairment affects 40-60% of people with MS, most ... read more

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