Featured Research

from universities, journals, and other organizations

Improved brain tumor diagnosis

Date:
September 19, 2012
Source:
Lancaster University
Summary:
New method of brain tumor diagnosis offers hope to tens of thousands of people.

UK scientists have made a breakthrough in a new method of brain tumour diagnosis, offering hope to tens of thousands of people.

Related Articles


Researchers, led by Professor Francis Martin of Lancaster University, have shown that infrared and Raman spectroscopy -- coupled with statistical analysis -- can be used to tell the difference between normal brain tissue and the different tumour types that may arise in this tissue, based on its individual biochemical-cell 'fingerprint'.

Spectroscopy is a technique that allows us to analyse light by breaking it into its component parts and studying the resulting pattern or spectrum.

Currently, when surgeons are operating to remove a brain tumour it can be difficult to spot where the tumour ends and normal tissue begins.

But new research published online in Analytical Methods this month has shown it is possible to spot the difference between diseased and normal tissue using Raman spectroscopy -- a type of spectroscopy which works effectively on living tissue, giving accurate results in seconds.

This is a key development which means it is now theoretically possible to test living tissue during surgery, helping doctors to remove the complete tumour whilst preserving intact adjacent healthy tissue.

The fingerprinting technique was also able to identify whether the tumours arose in the brain or whether they were secondary cancers arising from an unknown primary site. This is a key development which could help reveal previously undetected cancer elsewhere in the body, improving patient outcomes.

Professor Francis Martin said: "These are really exciting developments which could lead to significant improvements for individual patients diagnosed with brain tumours. We and other research teams are now working towards a sensor which can be used during brain surgery to give surgeons precise information about the tumour and tissue type that they are operating on."

The information obtained by this method can be combined with conventional methods, for example immunohistochemistry, to diagnose and grade brain tumours to allow for more accurate planning and execution of surgery and/or radiation therapy.

This offers more potential for individualised treatment and better long-term survival.


Story Source:

The above story is based on materials provided by Lancaster University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ketan Gajjar, Lara Heppenstall, Weiyi Pang, Katherine M Ashton, Julio Trevisan, Imran I Patel, Valon Llabjani, Helen F Stringfellow, Pierre L Martin-Hirsch, Tim Dawson, Francis L Martin. Diagnostic segregation of human brain tumours using Fourier-transform infrared and/or Raman spectroscopy coupled with discriminant analysis. Analytical Methods, 2012; DOI: 10.1039/C2AY25544H

Cite This Page:

Lancaster University. "Improved brain tumor diagnosis." ScienceDaily. ScienceDaily, 19 September 2012. <www.sciencedaily.com/releases/2012/09/120919124939.htm>.
Lancaster University. (2012, September 19). Improved brain tumor diagnosis. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2012/09/120919124939.htm
Lancaster University. "Improved brain tumor diagnosis." ScienceDaily. www.sciencedaily.com/releases/2012/09/120919124939.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins