Featured Research

from universities, journals, and other organizations

Pacemaker could help more heart failure patients

Date:
October 5, 2012
Source:
Karolinska Institutet
Summary:
A new study demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality. According to the team that carried out the study the discovery suggests that more heart-failure cases than the most serious could be helped by pacemakers.

A new study from Karolinska Institutet in Sweden demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality. According to the team that carried out the study, which is published in the scientific periodical The European Heart Journal, the discovery suggests that more heart-failure cases than the most serious could be helped by pacemakers.

Heart failure, which takes a multitude of forms, is one of the most common causes of hospitalisation and death in the West. While there are several effective treatments for weakened cardiac muscle contractility, there is as yet no tried and tested method for treating the reduced ability of the heart muscles to relax.

In the present study, a team comprising researchers at Sweden's Karolinska Institutet, Linkφping University, Stockholm South General Hospital and Karolinska University Hospital identified these two types of heart failure using data from the Swedish Heart Failure Registry. Their results show that a particular change in the ECG wave (which reflects the heart's electrical activity) is associated with a higher mortality rate amongst patients with heart failure. The anomaly, called the QRS prolongation (QRS being the characteristic peak-trough deflections of the ECG), indicates that the left and right sides of the heart are not cooperating as they should.

One way to treat the weakened cooperation that the QRS prolongation indicates is to insert a heart failure pacemaker, an advanced type of the device that sends signals to both the left and right sides of the heart. However, such a pacemaker is only used in the most severe cases. The researchers believe their study suggests that patients with milder forms of this type of heart failure can also be treated with a pacemaker.

"This advanced pacemaker has not yet been tried on heart failure caused by a reduced ability of the heart muscles to relax," says principal investigator docent Lars Lund. "However, our results indicate that it could be valuable for this type of heart failure too, and this possibility is something that we must now go on to explore."

The study was financed by the Swedish Heart Lung Foundation, the Stockholm County Council and the Swedish Association of Local Authorities and Regions.


Story Source:

The above story is based on materials provided by Karolinska Institutet. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lars H Lund, Juliane Jurga, Magnus Edner, Lina Benson, Ulf Dahlstrφm, Cecilia Linde, Urban Alehagen. Prevalence, Correlates and Prognostic Significance of QRS Prolongation in Heart Failure with Reduced and Preserved Ejection Fraction. European Heart Journal, 5 October 2012

Cite This Page:

Karolinska Institutet. "Pacemaker could help more heart failure patients." ScienceDaily. ScienceDaily, 5 October 2012. <www.sciencedaily.com/releases/2012/10/121005082541.htm>.
Karolinska Institutet. (2012, October 5). Pacemaker could help more heart failure patients. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2012/10/121005082541.htm
Karolinska Institutet. "Pacemaker could help more heart failure patients." ScienceDaily. www.sciencedaily.com/releases/2012/10/121005082541.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) — Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) — At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) — The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins