Featured Research

from universities, journals, and other organizations

Vigorous physical activity may increase risk of bleeding for children with hemophilia

Date:
October 9, 2012
Source:
American Medical Association (AMA)
Summary:
In children and adolescents with hemophilia, vigorous physical activity was associated with an elevated risk of bleeding, although it appears the absolute increase in risk may be small.

Hemophilia is a bleeding disorder that, if untreated, causes recurrent bleeding into joints. "Vigorous physical activity is thought to increase risk of bleeds in children with hemophilia, but the magnitude of the risk is unknown," according to background information in the article. Information about risks associated with physical activity is needed to help inform decisions regarding participation in physical activity, the authors write.

Carolyn R. Broderick, M.B.B.S., of the University of Sydney, Australia and colleagues conducted a study to quantify the transient (short duration) increase in risk of bleeding associated with vigorous physical activity in children with hemophilia. The study was conducted at three pediatric hemophilia centers in Australia between July 2008 and October 2010 and included 104 children and adolescent boys ages 4 through 18 years with moderate or severe hemophilia A or B who were monitored for bleeds for up to 1 year. Following each bleed, the child or parent was interviewed to determine exposures to physical activity preceding the bleed. Physical activity was categorized according to expected frequency and severity of collisions. The risk of bleeds associated with physical activity was estimated by contrasting exposure to physical activity in the 8 hours before the bleed with exposures in two 8-hour control (non-bleed) windows, controlling for levels of clotting factor in the blood. The median (midpoint) duration of follow-up was 52 weeks.

There were 436 bleeds, of which 336 were study bleeds (i.e., bleeding episodes without another bleeding episode in the preceding 2 weeks). Eighty-eight participants (84 percent) reported at least 1 bleed. The most frequent sites of bleeding were the knee (15 percent), ankle (14 percent), and elbow (10 percent). Compared with inactivity and category 1 activities (e.g., swimming), category 2 activities (e.g., basketball) were associated with a transient increase in the risk of bleeding (30.6 percent of bleed windows vs. 24.8 percent of first control windows; odds ratio, 2.7). Category 3 activities (e.g., wrestling) were associated with a greater transient increase in risk (7.0 percent of bleed windows vs. 3.4 percent of first control windows; odds ratio, 3.7). These odds of bleeding suggest that for most children, the absolute increase in risk associated with physical activity is low. "To illustrate absolute risk increase, for a child who bleeds 5 times annually and is exposed on average to category 2 activities twice weekly and to category 3 activities once weekly, exposure to these activities was associated with only 1 of the 5 annual bleeds," the authors write. Most bleeds associated with physical activity were present within an hour of activity.

"This study confirms that physical activity is associated with an increased risk of bleeds in children and adolescents with moderate or severe hemophilia A or B. It demonstrates that the relative increase in risk is moderate. However, for most children, the absolute increase in risk is likely to be low," the researchers conclude.


Story Source:

The above story is based on materials provided by American Medical Association (AMA). Note: Materials may be edited for content and length.


Journal Reference:

  1. Carolyn R. Broderick et al. Association Between Physical Activity and Risk of Bleeding in Children With Hemophilia. JAMA, 2012 DOI: 10.1001/jama.2012.12727

Cite This Page:

American Medical Association (AMA). "Vigorous physical activity may increase risk of bleeding for children with hemophilia." ScienceDaily. ScienceDaily, 9 October 2012. <www.sciencedaily.com/releases/2012/10/121009160706.htm>.
American Medical Association (AMA). (2012, October 9). Vigorous physical activity may increase risk of bleeding for children with hemophilia. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2012/10/121009160706.htm
American Medical Association (AMA). "Vigorous physical activity may increase risk of bleeding for children with hemophilia." ScienceDaily. www.sciencedaily.com/releases/2012/10/121009160706.htm (accessed August 27, 2014).

Share This




More Health & Medicine News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins