Featured Research

from universities, journals, and other organizations

Patient-reported outcomes essential to comparative effectiveness research

Date:
October 16, 2012
Source:
University of North Carolina Health Care
Summary:
Patient-reported outcomes should be a standard part of evaluating the comparative effectiveness of cancer treatments, according to recommendations put forward by a multi-institution research group.

Patient-reported outcomes should be a standard part of evaluating the comparative effectiveness of cancer treatments, according to recommendations put forward by a multi-institution research group.

Related Articles


In an early release article published this week online in the Journal of Clinical Oncology, a research group led by Ethan Basch, MD, Director of the Cancer Outcomes Research Program at UNC Lineberger Comprehensive Cancer Center, recommends that patient-reported symptoms and health-related quality of life measures should be assessed in comparative effectiveness studies designed to generate new evidence about cancer treatment. The article was written on behalf of the Center for Medical Technology Policy in Baltimore, MD.

Comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. The evidence is generated from research studies that compare drugs, medical devices, tests, surgeries, or ways to deliver health care.

"Comparative effectiveness research looks at how treatment options perform in a real-world setting, and is particularly important in cancer treatment, where patients are not only fighting their disease but also enduring treatments that may have a significant impact on their ability to function and their quality of life," said Basch.

"There is no way to adequately assess a treatment's impact on the patient without including their point of view, gleaned directly from asking about their experience in a consistent and scientifically-validated manner. Without this information, stakeholders -- including patients, physicians and nurses, payers, researchers and regulators -- have incomplete information for decision making about a given treatment."

The group recommends evaluation of a set of twelve core symptoms in studies in advanced or metastatic cancers, use of standard, validated measurements for patient-reported outcomes, to identify specific symptoms that may be relevant in studies of treatment for particular forms of cancer, and methods to gather the relevant data efficiently and effectively.

The recommendations were formulated when Dr. Basch was a member of Memorial Sloan-Kettering Cancer Center in New York.

Bryce Reeve, PhD, a member of UNC Lineberger and associate professor of health policy and management at UNC Gillings School of Global Public Health was also a member of the team. Other researchers include Amy Abernethy, MD, from Duke University, C. Daniel Mullins, PhD, from the University of Maryland, Mary Lou Smith, JD, MBA, from the Research Advocacy Network, Stephen J. Coons, PhD, from the University of Arizona, Jeff Sloan, PhD, from the Mayo Clinic, Cynthia Chauhan and Wayland Eppard from the North Central Cancer Treatment Group Patient Advocacy Committee, Keith Wenzel from Perceptive Informatics, Elizabeth S. Frank from Dana-Farber Cancer Institute, Stephen Raymond, PhD, from PHT Corporation and Joseph Lipscomb, PhD, from Emory University.


Story Source:

The above story is based on materials provided by University of North Carolina Health Care. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. Basch, A. P. Abernethy, C. D. Mullins, B. B. Reeve, M. L. Smith, S. J. Coons, J. Sloan, K. Wenzel, C. Chauhan, W. Eppard, E. S. Frank, J. Lipscomb, S. A. Raymond, M. Spencer, S. Tunis. Recommendations for Incorporating Patient-Reported Outcomes Into Clinical Comparative Effectiveness Research in Adult Oncology. Journal of Clinical Oncology, 2012; DOI: 10.1200/JCO.2012.42.5967

Cite This Page:

University of North Carolina Health Care. "Patient-reported outcomes essential to comparative effectiveness research." ScienceDaily. ScienceDaily, 16 October 2012. <www.sciencedaily.com/releases/2012/10/121016141657.htm>.
University of North Carolina Health Care. (2012, October 16). Patient-reported outcomes essential to comparative effectiveness research. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2012/10/121016141657.htm
University of North Carolina Health Care. "Patient-reported outcomes essential to comparative effectiveness research." ScienceDaily. www.sciencedaily.com/releases/2012/10/121016141657.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins