Featured Research

from universities, journals, and other organizations

New MRI technique allows detailed imaging of complex muscle structures and muscle damage

Date:
October 30, 2012
Source:
Eindhoven University of Technology
Summary:
Scientists have developed a technique that allows detailed 3-D imaging of complex muscle structures of patients. It also allows muscle damage to be detected very precisely. This new technique opens the way to much better and more patient-friendly diagnosis of muscular diseases. It also allows accurate, non-invasive muscle examinations among top athletes.

The muscles of the pelvic floor of a test subject.
Credit: Eindhoven University of Technology

Eindhoven University of Technology (TU/e) and the Academic Medical Center (AMC) in Amsterdam have together developed a technique that allows detailed 3-D imaging of complex muscle structures of patients. It also allows muscle damage to be detected very precisely. This new technique opens the way to much better and more patient-friendly diagnosis of muscular diseases. It also allows accurate, non-invasive muscle examinations among top athletes.

Froeling uses diffusion tensor imaging (DTI), an MRI technique that allows the movements of water molecules in living tissue to be viewed. Because muscles are made of fibers, the movements of water molecules in the direction of the fibers are different from those in other directions. This characteristic allows muscles to be imaged with a high level of detail. This was already possible on a small scale with simple muscles, but thanks to Froeling's work it can now also be done on a larger scale and with complex muscle structures. More importantly, this improved technique also reveals very small muscle damage, because of the different movements of the water molecules in damaged muscle fibers.

3-D images

To reach these results, Froeling improved the data acquisition process -- the way the MRI scanner images the muscle under examination. This has to be performed relatively quickly, because it is uncomfortable for patients to lie in an MRI scanner for a long time, but at the same time it has to provide sufficiently detailed data. He also improved the processing of the acquired data into reliable 3-D images. Physicians can now easily view complex muscle structures from all angles on-screen. No new equipment was needed; the researchers used standard widely available clinical systems.

Marathon runners

As a practical study, Froeling imaged a range of subjects including the thighs of marathon runners at different times: one week before a marathon, two days after it, and again three weeks after. He was able to visualize the muscle damage following the marathon. This was still visible after three weeks, even though the runners themselves in many cases no longer reported any pain in their muscles. Another study was of the pelvic floor in women; a good example of a highly complex muscle structure. The technique has proved to be capable of imaging this structure with great accuracy, which makes it potentially very valuable for the diagnosis of conditions such as uterine prolapse.

Wide application area

AMC Amsterdam and TU/e now intend to use this technique in studies of post polio syndrome and spinal muscular atrophy. Froeling believes there are numerous potential applications: there are around 600 different types of muscle disease and damage, and the new technique will improve the ability to study these. However further studies will first be needed: although the technique allows muscle disease or injury to be imaged it does not reveal the precise cause, which may be tearing, fat infiltration or other abnormalities. Clarification is also still needed on what are the normal values for healthy men and women of different ages, to provide a reference framework for identifying abnormalities in different groups of patients. Another kind of application is in examinations of top athletes, to allow timely detection of muscle damage or better estimation of the recovery time needed after injuries.

Martijn Froeling received a PhD for this research at TU/e on the 29th of October.


Story Source:

The above story is based on materials provided by Eindhoven University of Technology. Note: Materials may be edited for content and length.


Cite This Page:

Eindhoven University of Technology. "New MRI technique allows detailed imaging of complex muscle structures and muscle damage." ScienceDaily. ScienceDaily, 30 October 2012. <www.sciencedaily.com/releases/2012/10/121030142758.htm>.
Eindhoven University of Technology. (2012, October 30). New MRI technique allows detailed imaging of complex muscle structures and muscle damage. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2012/10/121030142758.htm
Eindhoven University of Technology. "New MRI technique allows detailed imaging of complex muscle structures and muscle damage." ScienceDaily. www.sciencedaily.com/releases/2012/10/121030142758.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins