Featured Research

from universities, journals, and other organizations

Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds

Date:
December 3, 2012
Source:
Canadian Medical Association Journal
Summary:
Women with polycystic ovary syndrome who are taking combined oral contraceptives have a two-fold risk of blood clots compared with women without the disorder who take contraceptives, according to a new study.

Women with polycystic ovary syndrome (PCOS) who are taking combined oral contraceptives have a 2-fold risk of blood clots compared with women without the disorder who take contraceptives, states a study published in CMAJ (Canadian Medical Association Journal).

Related Articles


PCOS affects between 6% and 10% of women of reproductive age with some estimates as high as 15%, making it the most common endocrine disorder in this age group. Risk factors for heart disease such as hypertension, diabetes, obesity and others are double among women with PCOS compared with women without the disorder. It is usually treated with combined oral contraceptives to regulate menstrual cycles and to help with acne and excessive hair growth associated with the condition. However, combined oral contraceptives are known to increase the risk of cardiovascular events.

Researchers from the US and Canada looked at 87 012 women aged 18 to 46 years in the US, half with PCOS and half as controls, to determine whether women with PCOS taking birth control pills are at increased risk of venous thromboembolism compared to matched contraceptive users. They excluded women with a history of heart disease, cancer and previous blood clots.

"We found a 2-fold increased risk of venous thromboembolism among women with PCOS taking combined oral contraceptives compared with matched controls," states Steven Bird, lead author and pharmacoepidemiologist with the Food and Drug Administration (FDA) in the United States, with coauthors. "We found a similar increased risk when we expanded the definition of PCOS by including its symptoms and treatment. We also found a 1.5-fold increased relative risk of venous thromboembolism among women with PCOS who were not taking contraceptives compared with matched controls."

"Our findings are consistent with the previously reported 2-fold increase in most of the risk factors for venous thromboembolism among women with PCOS."

"Physicians should consider the increased risk of venous thromboembolism when prescribing contraceptive therapy to women with PCOS," conclude the authors.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Steven T. Bird, Abraham G. Hartzema, James M. Brophy, Mahyar Etminan, Joseph A.C. Delaney. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. Canadian Medical Association Journal, 2012; DOI: 10.1503/cmaj.120677

Cite This Page:

Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. ScienceDaily, 3 December 2012. <www.sciencedaily.com/releases/2012/12/121203121638.htm>.
Canadian Medical Association Journal. (2012, December 3). Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2012/12/121203121638.htm
Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/12/121203121638.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) Denisa Livingston, a health advocate for the Din Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins