Featured Research

from universities, journals, and other organizations

Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds

Date:
December 3, 2012
Source:
Canadian Medical Association Journal
Summary:
Women with polycystic ovary syndrome who are taking combined oral contraceptives have a two-fold risk of blood clots compared with women without the disorder who take contraceptives, according to a new study.

Women with polycystic ovary syndrome (PCOS) who are taking combined oral contraceptives have a 2-fold risk of blood clots compared with women without the disorder who take contraceptives, states a study published in CMAJ (Canadian Medical Association Journal).

PCOS affects between 6% and 10% of women of reproductive age with some estimates as high as 15%, making it the most common endocrine disorder in this age group. Risk factors for heart disease such as hypertension, diabetes, obesity and others are double among women with PCOS compared with women without the disorder. It is usually treated with combined oral contraceptives to regulate menstrual cycles and to help with acne and excessive hair growth associated with the condition. However, combined oral contraceptives are known to increase the risk of cardiovascular events.

Researchers from the US and Canada looked at 87 012 women aged 18 to 46 years in the US, half with PCOS and half as controls, to determine whether women with PCOS taking birth control pills are at increased risk of venous thromboembolism compared to matched contraceptive users. They excluded women with a history of heart disease, cancer and previous blood clots.

"We found a 2-fold increased risk of venous thromboembolism among women with PCOS taking combined oral contraceptives compared with matched controls," states Steven Bird, lead author and pharmacoepidemiologist with the Food and Drug Administration (FDA) in the United States, with coauthors. "We found a similar increased risk when we expanded the definition of PCOS by including its symptoms and treatment. We also found a 1.5-fold increased relative risk of venous thromboembolism among women with PCOS who were not taking contraceptives compared with matched controls."

"Our findings are consistent with the previously reported 2-fold increase in most of the risk factors for venous thromboembolism among women with PCOS."

"Physicians should consider the increased risk of venous thromboembolism when prescribing contraceptive therapy to women with PCOS," conclude the authors.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Steven T. Bird, Abraham G. Hartzema, James M. Brophy, Mahyar Etminan, Joseph A.C. Delaney. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. Canadian Medical Association Journal, 2012; DOI: 10.1503/cmaj.120677

Cite This Page:

Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. ScienceDaily, 3 December 2012. <www.sciencedaily.com/releases/2012/12/121203121638.htm>.
Canadian Medical Association Journal. (2012, December 3). Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2012/12/121203121638.htm
Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/12/121203121638.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins