Featured Research

from universities, journals, and other organizations

Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds

Date:
December 3, 2012
Source:
Canadian Medical Association Journal
Summary:
Women with polycystic ovary syndrome who are taking combined oral contraceptives have a two-fold risk of blood clots compared with women without the disorder who take contraceptives, according to a new study.

Women with polycystic ovary syndrome (PCOS) who are taking combined oral contraceptives have a 2-fold risk of blood clots compared with women without the disorder who take contraceptives, states a study published in CMAJ (Canadian Medical Association Journal).

Related Articles


PCOS affects between 6% and 10% of women of reproductive age with some estimates as high as 15%, making it the most common endocrine disorder in this age group. Risk factors for heart disease such as hypertension, diabetes, obesity and others are double among women with PCOS compared with women without the disorder. It is usually treated with combined oral contraceptives to regulate menstrual cycles and to help with acne and excessive hair growth associated with the condition. However, combined oral contraceptives are known to increase the risk of cardiovascular events.

Researchers from the US and Canada looked at 87 012 women aged 18 to 46 years in the US, half with PCOS and half as controls, to determine whether women with PCOS taking birth control pills are at increased risk of venous thromboembolism compared to matched contraceptive users. They excluded women with a history of heart disease, cancer and previous blood clots.

"We found a 2-fold increased risk of venous thromboembolism among women with PCOS taking combined oral contraceptives compared with matched controls," states Steven Bird, lead author and pharmacoepidemiologist with the Food and Drug Administration (FDA) in the United States, with coauthors. "We found a similar increased risk when we expanded the definition of PCOS by including its symptoms and treatment. We also found a 1.5-fold increased relative risk of venous thromboembolism among women with PCOS who were not taking contraceptives compared with matched controls."

"Our findings are consistent with the previously reported 2-fold increase in most of the risk factors for venous thromboembolism among women with PCOS."

"Physicians should consider the increased risk of venous thromboembolism when prescribing contraceptive therapy to women with PCOS," conclude the authors.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Steven T. Bird, Abraham G. Hartzema, James M. Brophy, Mahyar Etminan, Joseph A.C. Delaney. Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis. Canadian Medical Association Journal, 2012; DOI: 10.1503/cmaj.120677

Cite This Page:

Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. ScienceDaily, 3 December 2012. <www.sciencedaily.com/releases/2012/12/121203121638.htm>.
Canadian Medical Association Journal. (2012, December 3). Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2012/12/121203121638.htm
Canadian Medical Association Journal. "Risk of blood clots two-fold for women with polycystic ovary syndrome taking combined oral contraceptives, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/12/121203121638.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.S. Ebola Response Measures Demonstrated

U.S. Ebola Response Measures Demonstrated

AP (Oct. 31, 2014) Officials in the Washington area showed off Ebola response measures being taken at Dulles International Airport and the National Institutes of Health. (Oct. 31) Video provided by AP
Powered by NewsLook.com
Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins