Featured Research

from universities, journals, and other organizations

Women with higher carotenoid levels have reduced risk of breast cancer

Date:
December 6, 2012
Source:
Journal of the National Cancer Institute
Summary:
Women with higher circulating carotenoid levels are at a reduced risk of breast cancer according to a new study.

Women with higher circulating carotenoid levels are at a reduced risk of breast cancer according to a study published December 6 in the Journal of the National Cancer Institute

Related Articles


Carotenoids, which are micronutrients found in fruits and vegetables, have been found to have anticarcinogenic properties. Previous experimental studies have shown that carotenoids inhibit the tumor progression and reduce proliferation of estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast cancers. Despite the inverse association between carotenoids and breast cancer in prior studies, the specific carotenoid has differed across multiple studies.

In order to determine the associations that specific carotenoids have with breast cancer, A. Heather Eliassen, Channing Division of Network Medicine, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, and colleagues, conducted a pooled analysis of eight cohort studies, which gathered over 80% of the world's published prospective data on plasma or serum carotenoids and breast cancer. The analysis included 3,055 case subjects and 3,956 matched control subjects. Participant carotenoid levels were recalibrated to a common standard to explain laboratory differences as well as to examine the differences across populations.

The researchers found that in over 3,000 case subjects, there were statistically significantly inverse associations between circulating levels of individual and total carotenoids and breast cancer risk, with a stronger finding in ER- breast cancers. "The inverse associations we observed among ER− tumors highlight carotenoids as one of the first modifiable risk factors for this poor prognosis tumor type," the authors write, adding that while some evidence has shown that carotenoids inhibit the growth of ER+ breast cancers as well, it's possible that its effect is hidden by hormone related associations which overpower other risk factors. Still, the researchers feel that, "A diet high in carotenoid-rich fruits and vegetables offers many health benefits, including a possible reduced risk of breast cancer."


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Women with higher carotenoid levels have reduced risk of breast cancer." ScienceDaily. ScienceDaily, 6 December 2012. <www.sciencedaily.com/releases/2012/12/121206163614.htm>.
Journal of the National Cancer Institute. (2012, December 6). Women with higher carotenoid levels have reduced risk of breast cancer. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2012/12/121206163614.htm
Journal of the National Cancer Institute. "Women with higher carotenoid levels have reduced risk of breast cancer." ScienceDaily. www.sciencedaily.com/releases/2012/12/121206163614.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins