Featured Research

from universities, journals, and other organizations

Number of multiple births affected by congenital anomalies has doubled since the 1980s

Date:
February 5, 2013
Source:
Wiley
Summary:
The number of congenital anomalies, or birth defects arising from multiple births has almost doubled since the 1980s, suggests a new study.

The number of congenital anomalies, or birth defects arising from multiple births has almost doubled since the 1980s, suggests a new study published February 6 in BJOG: An International Journal of Obstetrics and Gynaecology.

The study investigates how the change in the proportion of multiple births has affected the prevalence of congenital anomalies from multiple births, and the relative risk of congenital anomaly in multiple versus singleton births.

This study, led by the University of Ulster over a 24-year period (1984 -- 2007) across 14 European countries using data from birth registries, recorded 5.4 million births. Data from the European Surveillance of Congenital Anomalies (EUROCAT) was also used which includes congenital anomaly cases among live births, fetal deaths from 20 weeks gestation and terminations of pregnancy in fetal anomaly.

Results showed that within the European population studied, there was approximately a 50% rise in the multiple birth rate from 1984 to 2007. Of the 5.4 million births during the study period, 3.0% of babies were from multiple births. Of the total number of major congenital anomaly cases (148,359), 3.83% were from multiple births.

The study found that the prevalence of congenital anomalies from multiple births increased from 5.9 (1984 -- 1987) to 10.7 (2004 -- 2007) per 10,000 births.

Furthermore, the risk of congenital anomalies was 27% higher in multiple than singleton births, with this risk increasing over time. The authors indicate that this increase may be related to ART rather than multiple birth status.

Multiple births with congenital anomalies were more than twice as likely to be stillbirths compared to singleton births (4.6% compared to 1.8%) and more than twice as likely to be early neonatal deaths (5.45% compared to 2.51%). However, cases from multiple pregnancies were less likely to be terminations of pregnancy for fetal anomaly.

Professor Helen Dolk, from the Centre for Maternal Fetal and Infant Research, University of Ulster and co-author of the study said: "The co-occurrence of multiple birth and congenital anomaly among live borns places particular demands on parents and health services. This may be even more relevant for the one in nine affected twin pairs where both babies have a congenital anomaly.

"The increase in multiple birth rates may be explained by changes in maternal age and increased use of ART. It is clear that more research needs to be done to determine the contribution of ART to the risk of congenital anomalies in multiple births."

Dr Breidge Boyle of the University of Ulster, co-author of the study, added: "The adoption of a single embryo transfer (SET) policy may not reduce the number of babies with congenital anomalies but it may affect the pregnancy course and neonatal outcome and reduce extra demands placed on services and on parents by co-occurrence of multiple birth and congenital anomaly."

"John Thorp, BJOG Deputy-Editor-in-Chief added: "This increase in babies who are both from a multiple pregnancy and affected by a congenital anomaly has implications for pre and post natal service provision.

"Extra specialised help should be put in place for affected families, recognising than there are now nearly double as many affected families than there were 20 years ago."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Cite This Page:

Wiley. "Number of multiple births affected by congenital anomalies has doubled since the 1980s." ScienceDaily. ScienceDaily, 5 February 2013. <www.sciencedaily.com/releases/2013/02/130205200237.htm>.
Wiley. (2013, February 5). Number of multiple births affected by congenital anomalies has doubled since the 1980s. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2013/02/130205200237.htm
Wiley. "Number of multiple births affected by congenital anomalies has doubled since the 1980s." ScienceDaily. www.sciencedaily.com/releases/2013/02/130205200237.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins