Featured Research

from universities, journals, and other organizations

Pioneering research to manufacture cells from umbilical cord blood

Date:
February 7, 2013
Source:
University of Loughborough
Summary:
A new project to develop tools for the manufacture of large quantities of medically valuable cells from umbilical cord blood has been launched.

The cells in process of manufacture.
Credit: Image courtesy of University of Loughborough

A new project to develop tools for the manufacture of large quantities of medically valuable cells from umbilical cord blood has been launched by Loughborough University.

Dr Rob Thomas from the University's School of Mechanical and Manufacturing Engineering has been awarded a 1.3 million research fellowship by the Engineering and Physical Sciences Research Council (EPSRC) for the study.

The project could lead to new treatments for serious disease, and produce stocks of manufactured blood or platelets for transfusions. It may also form the basis of a manufactured blood bio-products industry.

Dr Thomas, a Senior Lecturer in Biomanufacturing, explains: "Within the next five years there will be substantial advances in treatments using cell based therapies. My proposed research will provide the manufacturing tools to enable the clinical community to deliver a new cohort of treatments for serious diseases to patients in the UK as well as support an important new economic activity in the UK. The work has evolved from projects in the EPSRC Centre for Innovative Manufacturing in Regenerative Medicine; a national collaboration led from Loughborough, and will continue to have many synergies with Centre projects."

Currently clinicians rely on donated supplies of umbilical cords collected nationally in banking programmes, but as new medical treatments using cord blood have been found, demand is rising and stocks are limited.

Umbilical cord blood contains immature cells with powerful properties to repair the human body. Cord blood is increasingly used instead of bone marrow to treat childhood blood cancers such as leukemia as there are fewer problems with rejection of the material. It is effective, or being trialled, to treat other serious conditions such as organ failure, childhood brain damage or diabetes.

Cord blood cells could also potentially be developed to generate large numbers of high value red blood cells or platelets for transfusion, or immune system cells for immunotherapies. The project, 'Engineering Biological Science -- Processes and Systems for Haematopoietic Stem Cell Based Therapy Manufacture' will use an engineering approach to grow blood cells in a controlled environment, test how physical conditions and chemical additives affect cell growth, and understand the relationships between cell development.

The aim of the study is to determine conditions required to grow cells in large, clinically useful numbers, and determine how tolerant the manufacturing process is for the repeated production of safe and effective cells.


Story Source:

The above story is based on materials provided by University of Loughborough. Note: Materials may be edited for content and length.


Cite This Page:

University of Loughborough. "Pioneering research to manufacture cells from umbilical cord blood." ScienceDaily. ScienceDaily, 7 February 2013. <www.sciencedaily.com/releases/2013/02/130207074214.htm>.
University of Loughborough. (2013, February 7). Pioneering research to manufacture cells from umbilical cord blood. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2013/02/130207074214.htm
University of Loughborough. "Pioneering research to manufacture cells from umbilical cord blood." ScienceDaily. www.sciencedaily.com/releases/2013/02/130207074214.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins