Featured Research

from universities, journals, and other organizations

Pioneering research to manufacture cells from umbilical cord blood

Date:
February 7, 2013
Source:
University of Loughborough
Summary:
A new project to develop tools for the manufacture of large quantities of medically valuable cells from umbilical cord blood has been launched.

The cells in process of manufacture.
Credit: Image courtesy of University of Loughborough

A new project to develop tools for the manufacture of large quantities of medically valuable cells from umbilical cord blood has been launched by Loughborough University.

Related Articles


Dr Rob Thomas from the University's School of Mechanical and Manufacturing Engineering has been awarded a 1.3 million research fellowship by the Engineering and Physical Sciences Research Council (EPSRC) for the study.

The project could lead to new treatments for serious disease, and produce stocks of manufactured blood or platelets for transfusions. It may also form the basis of a manufactured blood bio-products industry.

Dr Thomas, a Senior Lecturer in Biomanufacturing, explains: "Within the next five years there will be substantial advances in treatments using cell based therapies. My proposed research will provide the manufacturing tools to enable the clinical community to deliver a new cohort of treatments for serious diseases to patients in the UK as well as support an important new economic activity in the UK. The work has evolved from projects in the EPSRC Centre for Innovative Manufacturing in Regenerative Medicine; a national collaboration led from Loughborough, and will continue to have many synergies with Centre projects."

Currently clinicians rely on donated supplies of umbilical cords collected nationally in banking programmes, but as new medical treatments using cord blood have been found, demand is rising and stocks are limited.

Umbilical cord blood contains immature cells with powerful properties to repair the human body. Cord blood is increasingly used instead of bone marrow to treat childhood blood cancers such as leukemia as there are fewer problems with rejection of the material. It is effective, or being trialled, to treat other serious conditions such as organ failure, childhood brain damage or diabetes.

Cord blood cells could also potentially be developed to generate large numbers of high value red blood cells or platelets for transfusion, or immune system cells for immunotherapies. The project, 'Engineering Biological Science -- Processes and Systems for Haematopoietic Stem Cell Based Therapy Manufacture' will use an engineering approach to grow blood cells in a controlled environment, test how physical conditions and chemical additives affect cell growth, and understand the relationships between cell development.

The aim of the study is to determine conditions required to grow cells in large, clinically useful numbers, and determine how tolerant the manufacturing process is for the repeated production of safe and effective cells.


Story Source:

The above story is based on materials provided by University of Loughborough. Note: Materials may be edited for content and length.


Cite This Page:

University of Loughborough. "Pioneering research to manufacture cells from umbilical cord blood." ScienceDaily. ScienceDaily, 7 February 2013. <www.sciencedaily.com/releases/2013/02/130207074214.htm>.
University of Loughborough. (2013, February 7). Pioneering research to manufacture cells from umbilical cord blood. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2013/02/130207074214.htm
University of Loughborough. "Pioneering research to manufacture cells from umbilical cord blood." ScienceDaily. www.sciencedaily.com/releases/2013/02/130207074214.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins