Featured Research

from universities, journals, and other organizations

Common IV fluid associated with reduced likelihood of full recovery in patients with cardiac arrest

Date:
February 19, 2013
Source:
Public Library of Science
Summary:
Although an intravenous fluid that paramedics in Japan often give to patients in cardiac arrest before they reach hospital may help restore circulation, it may also be linked to reduced survival with minimal neurological or physical damage one month later, according to a new study.

Although an intravenous fluid that paramedics in Japan often give to patients in cardiac arrest before they reach hospital may help restore circulation, it may also be linked to reduced survival with minimal neurological or physical damage one month later, according to a study from Japan published in this week's PLOS Medicine.

In Japan, intravenous fluid loading with lactated Ringer's solution (a mixture of salts and sodium lactate) is included in resuscitation guidelines for patients who have a cardiac arrest out of hospital. In order to investigate outcomes associated with this practice, Japanese researchers, led by Akihito Hagihara from the Kyushu University Graduate School of Medicine, analysed national information from 2005 to 2009 on more than a half million patients experiencing a cardiac arrest out-of-hospital and then examined their subsequent health outcomes one month later.

The authors found that when other factors such as age, sex, and time taken for help to arrive were taken into account, the pre-hospital use of lactated Ringer's solution was linked to a slightly increased chance (1.2) of return of spontaneous circulation before arrival at hospital but with a decreased chance (0.7) of survival with minimal neurological or physical impairment one month later. However, among all patients, the pre-hospital use of lactated Ringer's solution had no effect on overall survival at one month.

Although these findings may have important clinical implications, the authors make clear that these results will need to be confirmed in other studies before changing clinical guidelines. Their study did not have information on the treatment that patients received once they reached hospital, which may have influenced the results.

The authors say: "We found that prehospital IV loading with lactated Ringer's solution was independently associated with a decreased likelihood of 1-month survival with minimal neurological or physical impairment."

They continue: "Prehospital IV loading with lactated Ringer's solution was associated with an increased likelihood of return of spontaneous circulation before hospital arrival, while 1-month survival varied depending on the analysis."

The authors add: "Our findings should be verified by studies that include data on in-hospital resuscitation."

They conclude: "Future studies will need to determine whether administration of fluids other than lactated Ringer's solution is associated with beneficial outcomes."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Akihito Hagihara, Manabu Hasegawa, Takeru Abe, Yoshifumi Wakata, Takashi Nagata, Yoshihiro Nabeshima. Prehospital Lactated Ringer's Solution Treatment and Survival in Out-of-Hospital Cardiac Arrest: A Prospective Cohort Analysis. PLoS Medicine, 2013; 10 (2): e1001394 DOI: 10.1371/journal.pmed.1001394

Cite This Page:

Public Library of Science. "Common IV fluid associated with reduced likelihood of full recovery in patients with cardiac arrest." ScienceDaily. ScienceDaily, 19 February 2013. <www.sciencedaily.com/releases/2013/02/130219172201.htm>.
Public Library of Science. (2013, February 19). Common IV fluid associated with reduced likelihood of full recovery in patients with cardiac arrest. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2013/02/130219172201.htm
Public Library of Science. "Common IV fluid associated with reduced likelihood of full recovery in patients with cardiac arrest." ScienceDaily. www.sciencedaily.com/releases/2013/02/130219172201.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins