Featured Research

from universities, journals, and other organizations

Bracelet-like device may control chronic acid reflux

Date:
February 20, 2013
Source:
Mayo Clinic
Summary:
A bracelet-like device with magnetic beads can control the chronic digestive disorder gastroesophageal reflux disease, according to a new study.

A bracelet-like device with magnetic beads can control the chronic digestive disorder gastroesophageal reflux disease, according to a study published online February 20 in the New England Journal of Medicine.

Related Articles


The device encircles the valve at the junction of the esophagus and stomach and helps it stay closed when a person is not eating or drinking. It eased symptoms in 92 of 100 patients with chronic acid reflux and allowed 87 percent of patients to stop using acid-suppressing drugs, third-year results from the five-year study showed. Ninety four percent of patients were satisfied with the treatment.

The advance is significant, says study co-author C. Daniel Smith, M.D., chair of the Surgery Department at Mayo Clinic in Florida and a specialist in treating reflux disease. Mayo Clinic is the only medical center in Florida and one of two in the Southeast to help study the device. Mayo Clinic in Arizona also offers treatment with the device.

"This is the first new, safe and effective treatment we have to treat reflux disease in 20 years," Dr. Smith says. "The device is simple, elegant and functional, and it provides an opportunity to help a very large number of patients. The only treatment options in the past have been acid-suppressing agents or surgery. Acid-suppressing agents don't directly address the underlying ineffective valve, leaving patients with persistent symptoms; surgery can lead to distressing side effects of bloating and inability to vomit in 20 percent of patients. These side effects occurred rarely with this new device."

Roughly 1 in 3 people in the United States have the chronic condition, the American Gastroenterological Association estimates. It can lead to serious health problems.

Acid reflux stems from a deficient or incompetent sphincter valve located at the bottom of the esophagus and the top of the stomach. The sphincter, a ring of muscle, normally stays constricted when a person is not eating; that prevents acid and other digestive juice from leaving the stomach and entering the esophagus.

If the muscle is too weak or relaxes inappropriately, stomach acid can work its way into the lining of the esophagus causing pain and burning -- commonly known as heartburn -- and regurgitation. These episodes can happen at any time, and in people of all ages.

Excessive acid can damage the esophagus and lead to a precancerous condition known as Barrett's esophagus and to esophageal cancer, which is rising rapidly in the U.S., Dr. Smith says. The epidemic of chronic acid reflux may explain the increase in cancer, he says. Dr. Smith has been offering the device to patients who qualify since March 2012, when the Food and Drug Administration approved it for use. He performs about 200 acid reflux-related surgeries a year.

Installation of the device is minimally invasive and takes one to two hours. After the procedure, patients stay overnight in the hospital.

Patients who may be helped by the device are those whose acid reflux is chronic with symptoms incompletely controlled by acid-suppressing drugs, Dr. Smith says.

Not all patients in the study fared well with the device. Serious adverse events occurred in six patients, and the device was removed in 4 patients without any significant long-term consequences. Dysphagia -- difficulty swallowing -- occurred in 68 percent of patients following installation of the device, but this side effect tapered off over time.

The study's lead researcher is Robert A. Ganz, M.D., from Minnesota Gastroenterology in Plymouth, Minn.

The study was supported by Torax Medical, which developed the LINX Reflux Management System. Mayo Clinic physicians and scientists helped Torax Medical develop the device, and Mayo Clinic licensed related technology to the company in exchange for equity. Dr. Smith and Ken DeVault, M.D., chair of the Department of Internal Medicine at Mayo Clinic in Florida, who also participated in this study, are paid consultants to Torax Medical.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. Robert A. Ganz, Jeffrey H. Peters, Santiago Horgan, Willem A. Bemelman, Christy M. Dunst, Steven A. Edmundowicz, John C. Lipham, James D. Luketich, W. Scott Melvin, Brant K. Oelschlager, Steven C. Schlack-Haerer, C. Daniel Smith, Christopher C. Smith, Dan Dunn, Paul A. Taiganides. Esophageal Sphincter Device for Gastroesophageal Reflux Disease. New England Journal of Medicine, 2013; 368 (8): 719 DOI: 10.1056/NEJMoa1205544

Cite This Page:

Mayo Clinic. "Bracelet-like device may control chronic acid reflux." ScienceDaily. ScienceDaily, 20 February 2013. <www.sciencedaily.com/releases/2013/02/130220184726.htm>.
Mayo Clinic. (2013, February 20). Bracelet-like device may control chronic acid reflux. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2013/02/130220184726.htm
Mayo Clinic. "Bracelet-like device may control chronic acid reflux." ScienceDaily. www.sciencedaily.com/releases/2013/02/130220184726.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com
Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins