Featured Research

from universities, journals, and other organizations

Screening could avert 12,000 lung cancer deaths each year in the United States

Date:
February 25, 2013
Source:
Wiley
Summary:
Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers has the potential to avert approximately 12,000 lung cancer deaths each year in the United States. By providing a national estimate of potentially avertable lung cancer deaths, the study will help policy makers better understand the possible benefits of LDCT lung cancer screening.

Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers has the potential to avert approximately 12,000 lung cancer deaths each year in the United States. That is the conclusion of a new analysis published early online in CANCER, a peer-reviewed journal of the American Cancer Society. By providing a national estimate of potentially avertable lung cancer deaths, the study will help policy makers better understand the possible benefits of LDCT lung cancer screening.

Despite substantial decreases in smoking prevalence, there are still 43 million Americans who are current smokers. If these smokers continue to smoke, half of them will die of smoking-related diseases including lung cancer; however, detecting lung cancer at an early stage can help prevent deaths.

The National Lung Screening Trial conducted from 2002 through 2009 found that, compared with chest x-ray, LDCT screening reduces lung cancer deaths by about 20 percent among current and former (quit within 15 years) smokers aged 55 to 74 years who have smoked at least 30 pack-years. (This equates to one pack per day for 30 years or two packs per day for 15 years).

Based on information from this trial combined with the US population size and other data, Jiemin Ma, PhD, of the American Cancer Society in Atlanta, and his colleagues concluded that in 2010, approximately 8.6 million Americans were eligible for LDCT screening for lung cancer according to the criteria used in the trial. When they combined this finding with information on lung cancer death rates, they estimated that if all screening-eligible Americans were to receive LDCT screening, approximately 12,000 lung cancer deaths would be delayed or prevented each year in the United States.

"Our findings provide a better understanding of the national-level impact of LDCT screening, which has the potential to save thousands of lives per year," said Dr. Ahmedin Jemal, a co-author of the paper. He added that since the publication of the National Lung Screening Trial results in 2011, several health organizations including the American Lung Association have recommended LDCT screening for lung cancer; however, some health agencies are still waiting for new data before making any recommendations.

In an accompanying editorial, Larry Kessler, ScD, of the University of Washington School of Public Health in Seattle, noted that while the study's findings are important, it is not clear whether a new national policy for lung cancer screening is warranted. "The high rate of false positive tests [from LDCT screening], and the related workup costs, and cost of treating findings that would not benefit patients give pause, and thus it is clear why a decision has not been yet taken in this direction," he wrote. He emphasized the importance of completing the full cost-benefit evaluations of the NLST and regardless of its outcome, the need for continued emphasis on smoking cessation efforts.


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal References:

  1. Jiemin Ma, Elizabeth M. Ward, Robert Smith, Ahmedin Jemal. Annual number of lung cancer deaths potentially avertable by screening in the United States. Cancer, 2013; DOI: 10.1002/cncr.27813
  2. Larry Kessler. Is 20% of a loaf enough? Cancer, 2013; DOI: 10.1002/cncr.27811

Cite This Page:

Wiley. "Screening could avert 12,000 lung cancer deaths each year in the United States." ScienceDaily. ScienceDaily, 25 February 2013. <www.sciencedaily.com/releases/2013/02/130225092244.htm>.
Wiley. (2013, February 25). Screening could avert 12,000 lung cancer deaths each year in the United States. ScienceDaily. Retrieved August 23, 2014 from www.sciencedaily.com/releases/2013/02/130225092244.htm
Wiley. "Screening could avert 12,000 lung cancer deaths each year in the United States." ScienceDaily. www.sciencedaily.com/releases/2013/02/130225092244.htm (accessed August 23, 2014).

Share This




More Health & Medicine News

Saturday, August 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins