Featured Research

from universities, journals, and other organizations

Overweight starting in early adulthood linked with kidney disease in older age

Date:
April 4, 2013
Source:
American Society of Nephrology (ASN)
Summary:
Individuals who are overweight starting in early adulthood are twice as likely to have chronic kidney disease at age 60 to 64 years than those who are not overweight. Larger waist-to-hip ratios (“apple-shaped” bodies) during middle age are also linked with chronic kidney disease at age 60 to 64 years.

Being overweight starting in young adulthood may significantly increase individuals' risks of developing kidney disease by the time they become seniors, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings emphasize the importance of excess weight as a risk factor for chronic kidney disease (CKD).

Because many populations across the globe continue to gain excess weight, Richard Silverwood, PhD, Dorothea Nitsch, MD (London School of Hygiene & Tropical Medicine, in England), and their colleagues conducted a study to see what sort of effect being overweight or obese might have on kidney health.

The researchers analyzed information from the Medical Research Council National Survey of Health and Development, a sample of children born in one week in March 1946 in England, Scotland, and Wales. A total of 4,584 participants had available data, including body mass index at ages 20, 26, 36, 43, 53, and 60 to 64 years.

Among the major findings:

• Participants who were overweight beginning early in adulthood (ages 26 or 36 years) were twice as likely to have CKD at age 60 to 64 years compared with those who first became overweight at age 60 to 64 years or never became overweight.

• The link between overweight and CKD was only in part explained by taking diabetes and hypertension into account.

• Larger waist-to-hip ratios ("apple-shaped" bodies) at ages 43 and 53 years were also linked with CKD at age 60 to 64 years.

"We estimated that 36% of CKD cases at age 60 to 64 in the current US population could be avoided if nobody became overweight until at least that age, assuming the same associations as in the analysis sample," said Dr. Nitsch. "To our knowledge we are the first to report how age of exposure to overweight across adulthood may affect kidney disease risk," she added.

It is unclear whether the timing of overweight onset or the duration of being overweight drives the link with CKD seen in the study. Either explanation suggests that preventing excess weight gain in early adulthood could have a considerable effect on the prevalence of CKD. Doing so appears to have a larger effect than any treatment for CKD known to date, the researchers said.


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. R. J. Silverwood, M. Pierce, C. Thomas, R. Hardy, C. Ferro, N. Sattar, P. Whincup, C. Savage, D. Kuh, D. Nitsch. Association between Younger Age When First Overweight and Increased Risk for CKD. Journal of the American Society of Nephrology, 2013; DOI: 10.1681/ASN.2012070675

Cite This Page:

American Society of Nephrology (ASN). "Overweight starting in early adulthood linked with kidney disease in older age." ScienceDaily. ScienceDaily, 4 April 2013. <www.sciencedaily.com/releases/2013/04/130404184430.htm>.
American Society of Nephrology (ASN). (2013, April 4). Overweight starting in early adulthood linked with kidney disease in older age. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/04/130404184430.htm
American Society of Nephrology (ASN). "Overweight starting in early adulthood linked with kidney disease in older age." ScienceDaily. www.sciencedaily.com/releases/2013/04/130404184430.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Newsy (July 30, 2014) The Peace Corps is one of several U.S.-based organizations to pull workers out of West Africa because of the Ebola outbreak. Video provided by Newsy
Powered by NewsLook.com
Weather Kills 2K A Year, But Storms Aren't The Main Offender

Weather Kills 2K A Year, But Storms Aren't The Main Offender

Newsy (July 30, 2014) Health officials say 2,000 deaths occur each year in the U.S. due to weather, but it's excessive heat and cold that claim the most lives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins