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Kids' allergies may correlate with omega-3, omega-6 lipid levels in cord blood

Date:
July 10, 2013
Source:
Public Library of Science
Summary:
Children with high proportions of poly-unsaturated fatty acids in cord blood at birth are more likely to develop respiratory and skin allergies in their early teens, according to new research.

Children with high proportions of poly-unsaturated fatty acids (PUFA) in cord blood at birth are more likely to develop respiratory and skin allergies in their early teens, according to research published July 10 in the open access journal PLOS ONE by Malin Barman and colleagues from the Chalmers University of Technology, Sweden.

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The researchers followed nearly 800 children born in 1996-97 for diagnosis of allergies at age 13, and studied a subset of 44 who were diagnosed with respiratory allergies, 37 with chronic skin rashes and 48 who did not suffer allergies. Cord blood samples taken at birth from these participants revealed that individuals who suffered allergies later in life had higher proportions of unsaturated fatty acids.

Children with allergies at age 13 had higher proportions of omega-3 and omega-6 PUFAs in cord blood samples taken at birth. Compared to healthy children, allergy sufferers also had lower levels of mono-unsaturated fats in their cord blood. The risk of respiratory allergies in children with higher PUFA levels was equally significant in children with allergic and non-allergic mothers. The study says, "The mechanism by which these lipids affect allergy development is unknown, but may involve dampening of the immune activation in infancy needed for proper maturation of the infant's immune system."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Malin Barman, Sara Johansson, Bill Hesselmar, Agnes E. Wold, Ann-Sofie Sandberg, Anna Sandin. High Levels of Both n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids in Cord Serum Phospholipids Predict Allergy Development. PLoS ONE, 2013; 8 (7): e67920 DOI: 10.1371/journal.pone.0067920

Cite This Page:

Public Library of Science. "Kids' allergies may correlate with omega-3, omega-6 lipid levels in cord blood." ScienceDaily. ScienceDaily, 10 July 2013. <www.sciencedaily.com/releases/2013/07/130710182936.htm>.
Public Library of Science. (2013, July 10). Kids' allergies may correlate with omega-3, omega-6 lipid levels in cord blood. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2013/07/130710182936.htm
Public Library of Science. "Kids' allergies may correlate with omega-3, omega-6 lipid levels in cord blood." ScienceDaily. www.sciencedaily.com/releases/2013/07/130710182936.htm (accessed March 27, 2015).

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