Featured Research

from universities, journals, and other organizations

Moderate exercise could be good for your tendons, research shows

Date:
August 7, 2013
Source:
University of East Anglia
Summary:
Moderate exercise could be good for keeping your tendons healthy, according to new research. The onset of tendon disease has previously been associated with exercise. However, new research shows that doing moderate exercise could help guard against, and treat, the painful and often debilitating condition.

Moderate exercise could be good for keeping your tendons healthy according to new research from the University of East Anglia funded by Arthritis Research UK.

Related Articles


The onset of tendon disease has previously been associated with exercise. However new research published n the journal Molecular Cell Research shows that doing moderate exercise could help guard against and treat the painful and often debilitating condition.

The research team showed that moving around decreases a group of enzymes (metalloproteinases) that degrade tendon tissue and increase tendon protein.

Tendon disease is caused by damage to a tendon at cellular level. Symptoms include chronic pain, inflammation, stiffness and reduced function.

Lead researcher Dr Eleanor Jones, from UEA's school of Biological Sciences, said: "The onset of tendon disease has always been associated with exercise, however this association has not been fully understood. We have shown that moderate exercise has a positive effect on tendons."

The team used human Achilles tendon cells which were seeded in rat tail collagen gels. These were then subjected to levels of strain experienced by human tendons to simulate moderate exercise.

"In this study we talk about moderately high exercise and we would consider running to be moderately high. But it's important to remember that our research was carried out in the lab so to confirm this we would need to complete further clinical studies."

The new findings also reveal how genes are regulated by the activation of the protein TGF-β (transforming growth factor beta). By investigating this pathway, researchers hope to find out more about how exercise is associated with tendon disease.


Story Source:

The above story is based on materials provided by University of East Anglia. Note: Materials may be edited for content and length.


Journal Reference:

  1. Eleanor R. Jones, Gavin C. Jones, Kirsten Legerlotz, Graham P. Riley. Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβ. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013; 1833 (12): 2596 DOI: 10.1016/j.bbamcr.2013.06.019

Cite This Page:

University of East Anglia. "Moderate exercise could be good for your tendons, research shows." ScienceDaily. ScienceDaily, 7 August 2013. <www.sciencedaily.com/releases/2013/08/130807125815.htm>.
University of East Anglia. (2013, August 7). Moderate exercise could be good for your tendons, research shows. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2013/08/130807125815.htm
University of East Anglia. "Moderate exercise could be good for your tendons, research shows." ScienceDaily. www.sciencedaily.com/releases/2013/08/130807125815.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins