Featured Research

from universities, journals, and other organizations

More accurate multiple sclerosis diagnostics possible

Date:
August 13, 2013
Source:
KTH The Royal Institute of Technology
Summary:
A group of proteins could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.

A group of proteins identified by researchers at Stockholm's KTH Royal Institute of Technology could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.

Like other autoimmune diseases, MS is complex and difficult to cure or to mitigate. At SciLifeLab in Stockholm, Peter Nilsson, professor in Proteomics at the School of Biotechnology, leads a group that that is looking for answers in large scale protein analysis.

By analysing tens of thousands of protein fragments for new autoimmunity biomarkers, or indicators, the group is identifying proteins that distinguish groups of MS patients according to the severity of the disease and how the disease develops over time. Their progress was published in the June 3 issue of Molecular & Cellular Proteomics.

"A group of 51 proteins have been identified as useful in future research around the diagnosis of MS," Nilsson says. "This is to study the origin of the disease and its development -- how severe it will be and how quickly it evolves over time."

As part of the Human Protein Atlas (HPA) project, Nilsson's group has access to more than 38,000 protein fragments. Nilsson says the HPA offers a unique resource that enables the team, which also includes Burcu Ayoglu, Anna Hδggmark, Mohsen Khademi, Tomas Olsson, Mathias Uhlιn and Jochen Schwenk, to continue their research with confidence.

"We expect a whole new field of research to open up around autoimmune disease, and with that, new insights," Nilsson says.

Ayoglu, a senior graduate student and researcher on the project, agrees that their work could yield much more knowledge about autoimmune diseases, such as hyperthyroidism, type 1 diabetes, vitiligo, rheumatoid arthritis, Sjogren's syndrome and psoriasis.

"Many autoimmune diseases are very complex and we currently lack complete knowledge of them," she says. "Most likely there are many more indicators to find. Our wide approach -- in which we study thousands of proteins -- is very suited to studying these autoimmune diseases."


Story Source:

The above story is based on materials provided by KTH The Royal Institute of Technology. Note: Materials may be edited for content and length.


Cite This Page:

KTH The Royal Institute of Technology. "More accurate multiple sclerosis diagnostics possible." ScienceDaily. ScienceDaily, 13 August 2013. <www.sciencedaily.com/releases/2013/08/130813112156.htm>.
KTH The Royal Institute of Technology. (2013, August 13). More accurate multiple sclerosis diagnostics possible. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2013/08/130813112156.htm
KTH The Royal Institute of Technology. "More accurate multiple sclerosis diagnostics possible." ScienceDaily. www.sciencedaily.com/releases/2013/08/130813112156.htm (accessed September 19, 2014).

Share This



More Mind & Brain News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Food Addiction Might Be Caused By PTSD

Food Addiction Might Be Caused By PTSD

Newsy (Sep. 18, 2014) — New research shows that women who suffer from PTSD are three times more likely to develop a food addiction. Video provided by Newsy
Powered by NewsLook.com
Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) — Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) — The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com
Shocker: Journalists Are Utterly Addicted To Coffee

Shocker: Journalists Are Utterly Addicted To Coffee

Newsy (Sep. 13, 2014) — A U.K. survey found that journalists consumed the most amount of coffee, but that's only the tip of the coffee-related statistics iceberg. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins