Featured Research

from universities, journals, and other organizations

More accurate multiple sclerosis diagnostics possible

Date:
August 13, 2013
Source:
KTH The Royal Institute of Technology
Summary:
A group of proteins could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.

A group of proteins identified by researchers at Stockholm's KTH Royal Institute of Technology could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.

Related Articles


Like other autoimmune diseases, MS is complex and difficult to cure or to mitigate. At SciLifeLab in Stockholm, Peter Nilsson, professor in Proteomics at the School of Biotechnology, leads a group that that is looking for answers in large scale protein analysis.

By analysing tens of thousands of protein fragments for new autoimmunity biomarkers, or indicators, the group is identifying proteins that distinguish groups of MS patients according to the severity of the disease and how the disease develops over time. Their progress was published in the June 3 issue of Molecular & Cellular Proteomics.

"A group of 51 proteins have been identified as useful in future research around the diagnosis of MS," Nilsson says. "This is to study the origin of the disease and its development -- how severe it will be and how quickly it evolves over time."

As part of the Human Protein Atlas (HPA) project, Nilsson's group has access to more than 38,000 protein fragments. Nilsson says the HPA offers a unique resource that enables the team, which also includes Burcu Ayoglu, Anna Hδggmark, Mohsen Khademi, Tomas Olsson, Mathias Uhlιn and Jochen Schwenk, to continue their research with confidence.

"We expect a whole new field of research to open up around autoimmune disease, and with that, new insights," Nilsson says.

Ayoglu, a senior graduate student and researcher on the project, agrees that their work could yield much more knowledge about autoimmune diseases, such as hyperthyroidism, type 1 diabetes, vitiligo, rheumatoid arthritis, Sjogren's syndrome and psoriasis.

"Many autoimmune diseases are very complex and we currently lack complete knowledge of them," she says. "Most likely there are many more indicators to find. Our wide approach -- in which we study thousands of proteins -- is very suited to studying these autoimmune diseases."


Story Source:

The above story is based on materials provided by KTH The Royal Institute of Technology. Note: Materials may be edited for content and length.


Cite This Page:

KTH The Royal Institute of Technology. "More accurate multiple sclerosis diagnostics possible." ScienceDaily. ScienceDaily, 13 August 2013. <www.sciencedaily.com/releases/2013/08/130813112156.htm>.
KTH The Royal Institute of Technology. (2013, August 13). More accurate multiple sclerosis diagnostics possible. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2013/08/130813112156.htm
KTH The Royal Institute of Technology. "More accurate multiple sclerosis diagnostics possible." ScienceDaily. www.sciencedaily.com/releases/2013/08/130813112156.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) — A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) — Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) — Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins