Featured Research

from universities, journals, and other organizations

Building better brain implants: The challenge of longevity

Date:
August 20, 2013
Source:
Journal of Visualized Experiments (JOVE)
Summary:
A new technique accommodates two challenges inherent in brain-implantation technology: gauging the property changes that occur during implantation and measuring them on a micro-scale.

In this experiment, we describe a method for environmentally-controlled microtensile testing of mechanically-adaptive polymer nanocomposites for ex-vivo characterization.
Credit: The Journal of Visualized Experiments

On August 20, JoVE, the Journal of Visualized Experiments will publish a technique from the Capadona Lab at Case Western Reserve University to accommodate two challenges inherent in brain-implantation technology, gauging the property changes that occur during implantation and measuring on a micro-scale. These new techniques open the doors for solving a great challenge for bioengineers -- crafting a device that can withstand the physiological conditions in the brain for the long-term.

Related Articles


"We created an instrument to measure the mechanical properties of micro-scale biomedical implants, after being explanted from living animals," explained the lab's principal investigator, Dr. Jeffrey R. Capadona. By preserving the changing properties that occurred during implantation even after removal, the technique offers potential to create and test new materials for brain implant devices. It could result in producing longer lasting and better suited devices for the highly-tailored functions.

For implanted devices, withstanding the high-temperatures, moisture, and other in-vivo properties poses a challenge to longevity. Resulting changes in stiffness, etc, of an implanted material can trigger a greater inflammatory response. "Often, the body's reaction to those implants causes the device to prematurely fail," says Dr. Capadona, "In some cases, the patient requires regular brain surgery to replace or revise the implants."

New implantation materials may help find solutions to restore motor function in individuals who have suffered from spinal cord injuries, stroke or multiple sclerosis. "Microelectrodes embedded chronically in the brain could hold promise for using neural activity to restore motor function in individuals who have, suffered from spinal cord injuries," said Dr. Capadona.

Furthermore, Capadona and his colleagues' method allows for measurement of mechanical properties using microsize scales. Previous methods typically require large or nano-sized samples of material, and data has to be scaled, which doesn't always work.

When asked why Dr. Capadona and his colleagues published their methods with JoVE, he responded "We choose JoVE because of the novel format to show readers visually what we are doing. If a picture is worth [a] thousand words, a video is worth a million."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments (JOVE). Note: Materials may be edited for content and length.


Journal Reference:

  1. Allison E. Hess, Kelsey A. Potter, Dustin J. Tyler, Christian A. Zorman, Jeffrey R. Capadona. Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization. Journal of Visualized Experiments, 2013; (78) DOI: 10.3791/50078

Cite This Page:

Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. ScienceDaily, 20 August 2013. <www.sciencedaily.com/releases/2013/08/130820094418.htm>.
Journal of Visualized Experiments (JOVE). (2013, August 20). Building better brain implants: The challenge of longevity. ScienceDaily. Retrieved March 1, 2015 from www.sciencedaily.com/releases/2013/08/130820094418.htm
Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. www.sciencedaily.com/releases/2013/08/130820094418.htm (accessed March 1, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Sunday, March 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rehab Robot Helps Restore Damaged Muscles and Nerves

Rehab Robot Helps Restore Damaged Muscles and Nerves

Reuters - Innovations Video Online (Mar. 1, 2015) A rehabilitation robot prototype to help restore deteriorated nerves and muscles using electromyography and computer games. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Elon Musk's Hyperloop Moves Forward

Elon Musk's Hyperloop Moves Forward

Buzz60 (Feb. 27, 2015) Zipping around at 800-miles an hour is coming closer to reality in California. An entire town is being built around Elon Musk&apos;s Hyperloop concept and it wants you to stop in for a ride when it&apos;s ready. Brett Larson is on board. Video provided by Buzz60
Powered by NewsLook.com
Vibrating Bicycle Senses Traffic

Vibrating Bicycle Senses Traffic

Reuters - Innovations Video Online (Feb. 26, 2015) Dutch scientists have developed a smart bicycle that uses sensors, wireless technology and video to warn riders of traffic dangers. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
In Japan, Robot Dogs Are for Life -- And Death

In Japan, Robot Dogs Are for Life -- And Death

AFP (Feb. 25, 2015) Robot dogs are the perfect pet for some in Japan who go to repairmen-turned-vets when their pooch breaks down - while a full Buddhist funeral ceremony awaits those who don&apos;t make it. Duration: 02:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins