Featured Research

from universities, journals, and other organizations

Building better brain implants: The challenge of longevity

Date:
August 20, 2013
Source:
Journal of Visualized Experiments (JOVE)
Summary:
A new technique accommodates two challenges inherent in brain-implantation technology: gauging the property changes that occur during implantation and measuring them on a micro-scale.

In this experiment, we describe a method for environmentally-controlled microtensile testing of mechanically-adaptive polymer nanocomposites for ex-vivo characterization.
Credit: The Journal of Visualized Experiments

On August 20, JoVE, the Journal of Visualized Experiments will publish a technique from the Capadona Lab at Case Western Reserve University to accommodate two challenges inherent in brain-implantation technology, gauging the property changes that occur during implantation and measuring on a micro-scale. These new techniques open the doors for solving a great challenge for bioengineers -- crafting a device that can withstand the physiological conditions in the brain for the long-term.

Related Articles


"We created an instrument to measure the mechanical properties of micro-scale biomedical implants, after being explanted from living animals," explained the lab's principal investigator, Dr. Jeffrey R. Capadona. By preserving the changing properties that occurred during implantation even after removal, the technique offers potential to create and test new materials for brain implant devices. It could result in producing longer lasting and better suited devices for the highly-tailored functions.

For implanted devices, withstanding the high-temperatures, moisture, and other in-vivo properties poses a challenge to longevity. Resulting changes in stiffness, etc, of an implanted material can trigger a greater inflammatory response. "Often, the body's reaction to those implants causes the device to prematurely fail," says Dr. Capadona, "In some cases, the patient requires regular brain surgery to replace or revise the implants."

New implantation materials may help find solutions to restore motor function in individuals who have suffered from spinal cord injuries, stroke or multiple sclerosis. "Microelectrodes embedded chronically in the brain could hold promise for using neural activity to restore motor function in individuals who have, suffered from spinal cord injuries," said Dr. Capadona.

Furthermore, Capadona and his colleagues' method allows for measurement of mechanical properties using microsize scales. Previous methods typically require large or nano-sized samples of material, and data has to be scaled, which doesn't always work.

When asked why Dr. Capadona and his colleagues published their methods with JoVE, he responded "We choose JoVE because of the novel format to show readers visually what we are doing. If a picture is worth [a] thousand words, a video is worth a million."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments (JOVE). Note: Materials may be edited for content and length.


Journal Reference:

  1. Allison E. Hess, Kelsey A. Potter, Dustin J. Tyler, Christian A. Zorman, Jeffrey R. Capadona. Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization. Journal of Visualized Experiments, 2013; (78) DOI: 10.3791/50078

Cite This Page:

Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. ScienceDaily, 20 August 2013. <www.sciencedaily.com/releases/2013/08/130820094418.htm>.
Journal of Visualized Experiments (JOVE). (2013, August 20). Building better brain implants: The challenge of longevity. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2013/08/130820094418.htm
Journal of Visualized Experiments (JOVE). "Building better brain implants: The challenge of longevity." ScienceDaily. www.sciencedaily.com/releases/2013/08/130820094418.htm (accessed October 23, 2014).

Share This



More Matter & Energy News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3D Printed Instruments Make Sweet Music in Sweden

3D Printed Instruments Make Sweet Music in Sweden

Reuters - Innovations Video Online (Oct. 23, 2014) Students from Lund University's Malmo Academy of Music are believed to be the world's first band to all use 3D printed instruments. The guitar, bass guitar, keyboard and drums were built by Olaf Diegel, professor of product development, who says 3D printing allows musicians to design an instrument to their exact specifications. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Chameleon Camouflage to Give Tanks Cloaking Capabilities

Chameleon Camouflage to Give Tanks Cloaking Capabilities

Reuters - Innovations Video Online (Oct. 22, 2014) Inspired by the way a chameleon changes its colour to disguise itself; scientists in Poland want to replace traditional camouflage paint with thousands of electrochromic plates that will continuously change colour to blend with its surroundings. The first PL-01 concept tank prototype will be tested within a few years, with scientists predicting that a similar technology could even be woven into the fabric of a soldiers' clothing making them virtually invisible to the naked eye. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Jet Sales Lift Boeing Profit 18 Pct.

Jet Sales Lift Boeing Profit 18 Pct.

Reuters - Business Video Online (Oct. 22, 2014) Strong jet demand has pushed Boeing to raise its profit forecast for the third time, but analysts were disappointed by its small cash flow. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Internet of Things Aims to Smarten Your Life

Internet of Things Aims to Smarten Your Life

AP (Oct. 22, 2014) As more and more Bluetooth-enabled devices are reaching consumers, developers are busy connecting them together as part of the Internet of Things. (Oct. 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins