Featured Research

from universities, journals, and other organizations

Estimate of a quarter of a million deaths annually vastly underestimates true burden of rheumatic heart disease

Date:
September 26, 2013
Source:
World Heart Federation
Summary:
A paper analyses the burden of disease and suggests that numbers published to date of global deaths from rheumatic heart disease (ranging from at least 233,000 deaths per year upwards) could be substantially underestimating reality, for a variety of reasons, most commonly lack of high quality (or in some cases any) data from high-prevalence countries and regions.

A paper in the RHD special issue of Global Heart, the journal of the World Heart Federation, analyses the burden of disease and suggests that numbers published to date (ranging from at least 233,000 deaths per year upwards) could be substantial underestimates for a variety of reasons, most commonly lack of high quality (or in some cases any) data from high-prevalence countries and regions. The paper is by Dr Liesl Zühlke, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa and Dr Andrew Steer, Centre for International Child Health at the University of Melbourne, Australia.

Related Articles


The authors say: "Currently available figures used to define the global burden of acute rheumatic fever and rheumatic heart disease, although crucial to control efforts, are imperfect. Data have been hindered by methodological differences between studies, by patchy coverage within countries and across regions, and by an incomplete understanding of the relationship between echocardiographic detection of asymptomatic mild disease and progression to symptomatic disease."

A WHO study published in 2005 found an overall global burden of 471,000 annual cases of ARF, with the incidence of acute rheumatic fever (ARF) ranging from 10 cases per 100,000 children aged 5 to 15 years in industrialised countries to 374 cases per 100,000 in the Pacific region. The overall burden of RHD was estimated to be 15.6 million prevalent cases with 282,000 new cases and over 233,000 deaths per year.

The recently published Global Burden of Disease Study reports that the number of years lived with disability (YLD) due to RHD was estimated in 2010 at 1 430 000*, equivalent to a quarter of the figure for all cancers combined. Lozarno and colleagues reported 345,100 deaths due to RHD in 2010 which represents a 25% reduction compared to 1990; with an age-standardised death rate of 5.2 per 100,000 which was a 53% reduction compared to1990. However, the authors caution that these figures should be viewed with caution and are currently being re-analysed for the next Global Burden of Disease analysis in 2014.

RHD burden of disease estimates also face the new problem of both more definite and borderline cases being diagnosed with echocardiogram equipment. The authors say: "It is perhaps time to change the way that we think about RHD and attempt to describe the disease burden with greater subtlety that takes into account our increasing understanding of the disease." Such a revised model might include an assessment of RHD burden in two categories: 1) Symptomatic disease which could also be called active disease; and 2) Asymptomatic disease which could also be called latent disease This approach has some similarities (but also obvious differences) to the model of disease applied to other latent diseases including infection with Mycobacterium tuberculosis.

The authors conclude: "Moving forward, it will be critical to generate high quality and comprehensive data regarding all aspects of the burden of ARF and RHD to better inform national, regional and global control strategies... New studies are underway in several high-prevalence sentinel areas in diverse geographic locations to address the need of contemporary data... These data will provide vital information in order to advocate even more strongly for directed funding and public health interventions to control ARF and RHD."


Story Source:

The above story is based on materials provided by World Heart Federation. Note: Materials may be edited for content and length.


Cite This Page:

World Heart Federation. "Estimate of a quarter of a million deaths annually vastly underestimates true burden of rheumatic heart disease." ScienceDaily. ScienceDaily, 26 September 2013. <www.sciencedaily.com/releases/2013/09/130926204714.htm>.
World Heart Federation. (2013, September 26). Estimate of a quarter of a million deaths annually vastly underestimates true burden of rheumatic heart disease. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2013/09/130926204714.htm
World Heart Federation. "Estimate of a quarter of a million deaths annually vastly underestimates true burden of rheumatic heart disease." ScienceDaily. www.sciencedaily.com/releases/2013/09/130926204714.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) — The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins