Featured Research

from universities, journals, and other organizations

Courses of prenatal corticosteroids not associated with increased death of children

Date:
October 14, 2013
Source:
American Medical Association (AMA)
Summary:
Multiple courses of prenatal corticosteroids, compared with a single course, taken by pregnant women to help prevent preterm birth was associated with no increase or decrease in the risk of death or disability for their children at age 5.

Multiple courses of prenatal corticosteroids, compared with a single course, taken by pregnant women to help prevent preterm birth was associated with no increase or decrease in the risk of death or disability for their children at age 5, according to a study published by JAMA Pediatrics, a JAMA Network publication.

Preterm birth (between 24 and 33 weeks) is a significant health problem and a single course of prenatal (also known as antenatal) corticosteroid therapy is recommended for women at risk of preterm birth. Questions remain about whether additional courses of corticosteroids might be safe and beneficial, the authors write in the study background.

Elizabeth V. Asztalos, M.D., of the Sunnybrook Health Sciences Centre, Toronto, Canada, and colleagues examined the effects of single vs. multiple courses of corticosteroids on the risk of death and neurodevelopmental disability (including cerebral palsy, blindness, deafness or abnormal attention or behavior) in children of mothers who participated in the Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study (MACS). The follow-up study included more than 1,700 mothers and their children.

Study findings indicate no difference in the risk of death or neurodevelopmental disability: 217 of 871 children (24.9 percent) in the multiple-courses group vs. 210 of the 848 children (24.8 percent) in the single-course group.

“Multiple courses, compared with a single course, of antenatal corticosteroid therapy did not increase or decrease the risk of death or disability at 5 years of age. Because of a lack of strong conclusive evidence of short-term or long-term benefits, it remains our opinion that multiple courses should not be recommended in women with ongoing risk of preterm birth,” the study concludes.


Story Source:

The above story is based on materials provided by American Medical Association (AMA). Note: Materials may be edited for content and length.


Journal Reference:

  1. Elizabeth V. Asztalos. Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study. JAMA Pediatrics, 2013; DOI: 10.1001/jamapediatrics.2013.2764

Cite This Page:

American Medical Association (AMA). "Courses of prenatal corticosteroids not associated with increased death of children." ScienceDaily. ScienceDaily, 14 October 2013. <www.sciencedaily.com/releases/2013/10/131014221505.htm>.
American Medical Association (AMA). (2013, October 14). Courses of prenatal corticosteroids not associated with increased death of children. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2013/10/131014221505.htm
American Medical Association (AMA). "Courses of prenatal corticosteroids not associated with increased death of children." ScienceDaily. www.sciencedaily.com/releases/2013/10/131014221505.htm (accessed October 22, 2014).

Share This



More Health & Medicine News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins