Featured Research

from universities, journals, and other organizations

Exercise during pregnancy improves vascular function of offspring into adulthood

Date:
October 24, 2013
Source:
Wiley
Summary:
Exercise during gestation has the potential to program vascular health in offspring into their adulthood, in particular significantly altering the vascular smooth muscle.

Exercise during gestation has the potential to program vascular health in offspring into their adulthood, in particular significantly altering the vascular smooth muscle, shows a new study published in the journal Experimental Physiology.

The current guidelines for pregnant women recommend thirty minutes of moderate intensity physical activity on most if not all days of the week. Unfortunately, not all physicians are yet convinced that exercise is beneficial for both the pregnant women and their offspring.

The results of this study provide evidence that maternal exercise during pregnancy is a powerful programming stimulus in the arteries of the offspring and that this programming may have implications for future cardiovascular disease susceptibility of the offspring.

Previous studies only focused on offspring at an early age, so this study is the first to demonstrate the effects of exercise on adult offspring.

Dr Sean Newcomer, of California State University San Marcos USA, and Dr Bahls, of Universitätsmedizin Greifswald Germany say:

"Our study was the first to demonstrate that maternal exercise during pregnancy significantly impacts vascular function in adult offspring."

"A second important aspect of the findings in our study is that previous research identified the endothelium, which is the single-cell layer lining all blood vessels, to be susceptible to foetal-programming interventions. Contrarily, we show that the vascular smooth muscle was significantly altered in adult offspring from exercise trained mothers."

The research took place in pigs as they have human-like responses to physical activity and can be trained to complete exercise regimens, whilst avoiding the time and ethical constraints of long-term studies in humans.

Drs Newcomer and Bahls explain how they carried out the research:

"Swine are considered a superior animal model for cardiovascular studies compared to rodents. Pregnant swine were treadmill exercised for 20-45 minutes for five days a week, which is consistent with American Congress of Obstetricians and Gynaecologists

(ACOG) recommendations. We assessed vascular function in offspring femoral arteries using in vitro techniques."

Future research, especially in humans, is essential to not only improve biological understanding of how exercise during pregnancy alters adult offspring health, but also to ensure evidence-based guidelines for pregnant women.

Drs Newcomer and Bahls say:

"We are only starting to understand how exercise during gestation influences offspring adult health and disease. Results like ours may help to create guidelines enabling women to make the best decisions for them and their children by providing evidence based health choices.

"Physical activity may act through multiple pathways which depend on type, duration, intensity and frequency of the exercise regimen. Furthermore, it is essential that future research investigates the coronary circulation and also establishes what impact these reported changes in vascular function in the offspring have on cardiovascular disease susceptibility."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Martin Bahls, Ryan D Sheldon, Pardis Taheripour, Kerry a Clifford, Kallie B Foust, Emily D Breslin, Jeremy N Marchant-Forde, Ryan a Cabot, M Harold Laughlin, Christopher a Bidwell, and Sean C Newcomer. Mothers' exercise during pregnancy programs vasomotor function in adult offspring. Experimental Physiology, October 2013

Cite This Page:

Wiley. "Exercise during pregnancy improves vascular function of offspring into adulthood." ScienceDaily. ScienceDaily, 24 October 2013. <www.sciencedaily.com/releases/2013/10/131024220916.htm>.
Wiley. (2013, October 24). Exercise during pregnancy improves vascular function of offspring into adulthood. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2013/10/131024220916.htm
Wiley. "Exercise during pregnancy improves vascular function of offspring into adulthood." ScienceDaily. www.sciencedaily.com/releases/2013/10/131024220916.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) — A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com
How The 'Angelina Jolie Effect' Increased Cancer Screenings

How The 'Angelina Jolie Effect' Increased Cancer Screenings

Newsy (Sep. 19, 2014) — Angelina's Jolie's decision to undergo a preventative mastectomy in 2013 inspired many women to seek early screenings for the disease. Video provided by Newsy
Powered by NewsLook.com
The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) — As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins