Featured Research

from universities, journals, and other organizations

Risk of osteoporosis drug's side effects not significant

Date:
October 30, 2013
Source:
Loyola University Health System
Summary:
The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers.

The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers at Loyola University Health System (LUHS). These findings were presented earlier this month at the American Society for Bone and Mineral Research's annual meeting.

"Osteoporosis is a growing problem in this country," said Laurae Hicks, first author and Stritch School of Medicine medical student. "These findings are valuable for the millions of Americans who suffer from osteoporosis and are considering their treatment options."

Zoledronic acid is commonly used to treat osteoporosis. The treatment strengthens bones by increasing the process by which bone is broken down and replaced with new bone tissue. While this medication is effective at preventing and treating osteoporosis, potential side effects include kidney failure and hypocalcemia.

Kidney failure occurs when the kidneys fail to adequately filter waste products from the blood while hypocalcemia is characterized by low calcium levels in the blood. This condition can lead to a variety of symptoms, including weakness, muscle cramps, excessive nervousness, headaches or uncontrollable twitching and cramping in certain muscles.

"This study helped us determine the severity and prevalence of these side effects," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center. "This will help us assess which patients are good candidates for this treatment."

Researchers studied 237 patients before and after they received injections of zoledronic acid. They found that a slight and clinically insignificant decline in calcium levels may be seen after the first infusion, but these effects appear to be transient. The findings apply only to individuals with normal vitamin D levels and kidney function prior to infusion and cannot be generalized to those with renal insufficiency and existing calcium and vitamin D deficiencies.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "Risk of osteoporosis drug's side effects not significant." ScienceDaily. ScienceDaily, 30 October 2013. <www.sciencedaily.com/releases/2013/10/131030185355.htm>.
Loyola University Health System. (2013, October 30). Risk of osteoporosis drug's side effects not significant. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2013/10/131030185355.htm
Loyola University Health System. "Risk of osteoporosis drug's side effects not significant." ScienceDaily. www.sciencedaily.com/releases/2013/10/131030185355.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins