Featured Research

from universities, journals, and other organizations

Risk of osteoporosis drug's side effects not significant

Date:
October 30, 2013
Source:
Loyola University Health System
Summary:
The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers.

The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers at Loyola University Health System (LUHS). These findings were presented earlier this month at the American Society for Bone and Mineral Research's annual meeting.

Related Articles


"Osteoporosis is a growing problem in this country," said Laurae Hicks, first author and Stritch School of Medicine medical student. "These findings are valuable for the millions of Americans who suffer from osteoporosis and are considering their treatment options."

Zoledronic acid is commonly used to treat osteoporosis. The treatment strengthens bones by increasing the process by which bone is broken down and replaced with new bone tissue. While this medication is effective at preventing and treating osteoporosis, potential side effects include kidney failure and hypocalcemia.

Kidney failure occurs when the kidneys fail to adequately filter waste products from the blood while hypocalcemia is characterized by low calcium levels in the blood. This condition can lead to a variety of symptoms, including weakness, muscle cramps, excessive nervousness, headaches or uncontrollable twitching and cramping in certain muscles.

"This study helped us determine the severity and prevalence of these side effects," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center. "This will help us assess which patients are good candidates for this treatment."

Researchers studied 237 patients before and after they received injections of zoledronic acid. They found that a slight and clinically insignificant decline in calcium levels may be seen after the first infusion, but these effects appear to be transient. The findings apply only to individuals with normal vitamin D levels and kidney function prior to infusion and cannot be generalized to those with renal insufficiency and existing calcium and vitamin D deficiencies.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "Risk of osteoporosis drug's side effects not significant." ScienceDaily. ScienceDaily, 30 October 2013. <www.sciencedaily.com/releases/2013/10/131030185355.htm>.
Loyola University Health System. (2013, October 30). Risk of osteoporosis drug's side effects not significant. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2013/10/131030185355.htm
Loyola University Health System. "Risk of osteoporosis drug's side effects not significant." ScienceDaily. www.sciencedaily.com/releases/2013/10/131030185355.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins