Featured Research

from universities, journals, and other organizations

Computer-aided image analysis for breast tumor diagnosis

Date:
November 4, 2013
Source:
SPIE--International Society for Optics and Photonics
Summary:
Researchers hope radiologists will be able to routinely incorporate computer-aided image analysis and diagnosis in identifying tumor characteristics and forming patient-specific breast cancer treatment plans. Their approach uses data to identify how tumor characteristics apply to disease states, which could lead to the comparison of a tumor's characteristics with thousands of similar cases.

Above, the quantitative image analysis workstation in the Giger laboratory for assessing breast lesions observed in MRIs, showing automated lesion segmentation, feature extraction (volumetrics, morphology, texture, kinetics), and estimation of the probability of malignancy.
Credit: SPIE

Researchers at the University of Chicago are developing computer-aided diagnosis (CADx) and quantitative image analysis (QIA) methods for mammograms, ultrasounds and magnetic resonance images (MRIs) to identify specific tumor characteristics, including size, shape and sharpness, said lead researcher Maryellen Giger, A.N. Pritzker Professor of Radiology/Medical Physics and director of the Imaging Research Institute at the University of Chicago.

Currently, computer-aided detection provides a "second opinion" to a radiologist in locating suspicious regions within mammograms. Next, radiologists will ultimately be able to use computer-extracted lesion characteristics when performing a diagnosis to assess whether the tumor is cancerous.

The role of quantitative image analysis is expanding beyond screening and toward application of risk assessment, diagnosis, prognosis, and response to therapy, and in using data to identify how tumor characteristics apply to disease states, Giger said.

This could lead to the comparison of a tumor's characteristics with thousands of similar cases, enabling the exploration of complex relationships among tumor characteristics across large populations, which may ultimately contribute to the design of patient-specific treatments. It could also be used to study the association between a tumor's observable characteristics and cell-level data for the emerging field of imaging and genomics, which aims to identify genes that influence the risk for disease.

While results are promising for digital mammograms, researchers are extending their analysis to breast ultrasounds and MRIs due to the need for clinical validation within a larger screening population.

Through studies between image-based characteristics and genomics, investigators will potentially be able to determine which tumor characteristics are related to and which complement genetic findings, with the ultimate goal of merging them to include both genetic and environmental contributions in clinical decisions. Researchers are now using data-mining methods to identify those potential relationships.

A paper titled "Quantitative breast image analysis for personalized medicine" describing the work by Giger was published 14 October in the SPIE Newsroom.


Story Source:

The above story is based on materials provided by SPIE--International Society for Optics and Photonics. Note: Materials may be edited for content and length.


Journal Reference:

  1. Maryellen Giger. Quantitative breast image analysis for personalized medicine. SPIE Newsroom, 2013; DOI: 10.1117/2.1201310.005139

Cite This Page:

SPIE--International Society for Optics and Photonics. "Computer-aided image analysis for breast tumor diagnosis." ScienceDaily. ScienceDaily, 4 November 2013. <www.sciencedaily.com/releases/2013/11/131104142426.htm>.
SPIE--International Society for Optics and Photonics. (2013, November 4). Computer-aided image analysis for breast tumor diagnosis. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2013/11/131104142426.htm
SPIE--International Society for Optics and Photonics. "Computer-aided image analysis for breast tumor diagnosis." ScienceDaily. www.sciencedaily.com/releases/2013/11/131104142426.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins