Featured Research

from universities, journals, and other organizations

More aggressive management needed for children with refractory convulsive status epilepticus

Date:
December 8, 2013
Source:
American Epilepsy Society (AES)
Summary:
The management of refractory convulsive status epilepticus (RCSE) varies at different medical centers and from patient to patient. Rapid success in aborting these non-stop seizures is crucial as the risk of neurological damage is high and, though rare, may result in death depending on seizure duration. By pooling data and analyzing current RCSE management practices, researchers conducted a study that could lead to improved treatment outcomes for potentially life-threatening seizures.

The management of refractory convulsive status epilepticus (RCSE) varies at different medical centers and from patient to patient. Rapid success in aborting these non-stop seizures is crucial as the risk of neurological damage is high and, though rare, may result in death depending on seizure duration. By pooling data and analyzing current RCSE management practices, researchers representing a multicenter network of tertiary referral hospitals in the U.S. conducted a study that could lead to improved treatment outcomes for potentially life-threatening seizures.

The network of hospitals [The Pediatric Status Epilepticus Research Group (pSERG)] sought to describe the care of children with RCSE, looking closely at the type of medications prescribed, order of administration, and the duration between seizure onset and drug administration.

In a report presented today at the American Epilepsy Society's 67th Annual Meeting, pSERG investigators analyzed 74 RCSE episodes in 72 children. The mean patient age for refractory seizures was 2.5 years (range 1-7 yrs.). Most RCSE episodes (56) began outside of the hospital and more than half of those (33) occurred in children without prior history of seizures.

"Our study suggests prominent variability in current anticonvulsant drug (AED) choices in a network of leading reference hospitals in the United States," said Tobias Loddenkemper, M.D., of Boston Children's Hospital and Harvard Medical School, who presented the report. "Escalation of one type of anticonvulsant to the next and, especially, the timing of drug administration left room for improvement. Our data provide a framework to do better in the care of pediatric patients with convulsive status epilepticus and highlight opportunities to be more aggressive and effective."

The group expects to conduct future collaborations that may allow for the collection of biologic samples to determine genetic factors and provide information for future interventional trials.


Story Source:

The above story is based on materials provided by American Epilepsy Society (AES). Note: Materials may be edited for content and length.


Cite This Page:

American Epilepsy Society (AES). "More aggressive management needed for children with refractory convulsive status epilepticus." ScienceDaily. ScienceDaily, 8 December 2013. <www.sciencedaily.com/releases/2013/12/131208133408.htm>.
American Epilepsy Society (AES). (2013, December 8). More aggressive management needed for children with refractory convulsive status epilepticus. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/12/131208133408.htm
American Epilepsy Society (AES). "More aggressive management needed for children with refractory convulsive status epilepticus." ScienceDaily. www.sciencedaily.com/releases/2013/12/131208133408.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins