Featured Research

from universities, journals, and other organizations

Natural substance studied for future treatment of possibly incurable childhood cancer

Date:
January 13, 2014
Source:
Expertsvar
Summary:
In a recent doctoral thesis, a researcher shows how the substance ellagic acid found in red berries and nuts, for instance, can stop cell division in cultivated cells from the childhood cancer neuroblastoma and induce cell death.

In a recent doctoral thesis submitted at Karlstad University, Christina Fjæraa Alfredsson shows how the substance ellagic acid found in red berries and nuts, for instance, can stop cell division in cultivated cells from the childhood cancer neuroblastoma and induce cell death.

In their laboratory experiments Christina Fjæraa Alfredsson and her colleagues have studied how ellagic acid affects the growth and survival of cultivated neuroblastoma cells. An important discovery was that adding ellagic acid resulted in a so-called programmed cell death.

"The number of tumour cells in our model system was drastically reduced after the addition of ellagic acid. The effect was dose dependent, so at the rate of reduced cell growth and cell adhesion, and thus less potential for growth, the number of cell deaths increased considerably," says Christina Fjæraa Alfredsson.

Research on cancer treatment

The results are expected to form the basis for further research on ellagic acid and the possibility to use the substance in the future as a complement to current treatments of neuroblastoma and other forms of cancer.

"Many years of research remain before we know if ellagic acid can be used clinically," says Christina Fjæraa Alfredsson.

Strong antioxidant for use in future medicinal products

Ellagic acid is a naturally occurring substance and belongs to the group of phytochemicals, which are substances that can be extracted from plants. Pomegranates, raspberries, strawberries, and walnuts are rich in ellagic acid. Ellagic acid and similar substances are mostly known as strong antioxidants and therefore potentially effective against various diseases, but today researchers are also interested in how ellagic acid can be used in future medicinal products for treating cancer, for example.

The third most common childhood cancer disease

Neuroblastoma is the third most common childhood cancer type in children under the age of one. Aggressive neuroblastoma is a difficult cancer type to treat, and in spite of intensive research, the death rate for this type of neuroblastoma is still very high compared with other cancer types. It is therefore crucial to develop complementary alternatives to the current methods of treatment.


Story Source:

The above story is based on materials provided by Expertsvar. Note: Materials may be edited for content and length.


Cite This Page:

Expertsvar. "Natural substance studied for future treatment of possibly incurable childhood cancer." ScienceDaily. ScienceDaily, 13 January 2014. <www.sciencedaily.com/releases/2014/01/140113100449.htm>.
Expertsvar. (2014, January 13). Natural substance studied for future treatment of possibly incurable childhood cancer. ScienceDaily. Retrieved September 24, 2014 from www.sciencedaily.com/releases/2014/01/140113100449.htm
Expertsvar. "Natural substance studied for future treatment of possibly incurable childhood cancer." ScienceDaily. www.sciencedaily.com/releases/2014/01/140113100449.htm (accessed September 24, 2014).

Share This



More Health & Medicine News

Wednesday, September 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Costs Keep Mounting

Ebola Costs Keep Mounting

Reuters - Business Video Online (Sep. 23, 2014) — The WHO has warned up to 20,000 people could be infected with Ebola over the next few weeks. As Sonia Legg reports, the implications for the West African countries suffering from the disease are huge. Video provided by Reuters
Powered by NewsLook.com
Ebola Cases Could Reach 1.4 Million Within 4 Months

Ebola Cases Could Reach 1.4 Million Within 4 Months

Newsy (Sep. 23, 2014) — Health officials warn that without further intervention, the number of Ebola cases in Liberia and Sierra Leone could reach 1.4 million by January. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Cases to Triple in Weeks Without Drastic Action

WHO: Ebola Cases to Triple in Weeks Without Drastic Action

AFP (Sep. 23, 2014) — The number of Ebola infections will triple to 20,000 by November, soaring by thousands every week if efforts to stop the outbreak are not stepped up radically, the WHO warned in a study on Tuesday. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
5 Ways Men Can Prevent Most Heart Attacks

5 Ways Men Can Prevent Most Heart Attacks

Newsy (Sep. 23, 2014) — No surprise here: A recent study says men can reduce their risk of heart attack by maintaining a healthy lifestyle, which includes daily exercise. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins